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Comparison of patients with renal cell carcinoma in adjuvant therapy trials to a real-world population

Millan B, Breau RH, Mallick R, Wood L, Rendon R, Finelli A, So AI, Lavallée LT, Pouliot F, Bhindi B, Heng D, Drachenberg D, Tanguay S, Dean L, Basappa NS, Lattouf J-B, Bjarnason G, Lalani A-K, Kapoor A. Comparison of patients with renal cell carcinoma in adjuvant therapy trials to a real-world population. Urologic Oncology Seminars and Original Investigations. 2023 May 16;S1078-1439(23)00133-3.

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Cardiovascular events among recipients of hematopoietic stem cell transplantation-A systematic review and meta-analysis

Aghel N, Lui M, Wang V, Khalaf D, Mian H, Hillis C, Walker I, Leber B, Lipton JH, Aljama M, Lepic K, Berg T, Garcia-Horton A, Petropoulos J, Masoom H, Leong DP. Cardiovascular events among recipients of hematopoietic stem cell transplantation-A systematic review and meta-analysis. Bone Marrow Transplantation. 2023 May; 58(5) 478-490

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Circulating Tumor DNA as a Predictive Biomarker for Clinical Outcomes With Margetuximab and Pembrolizumab in Pretreated HER2-Positive Gastric/ Gastroesophageal Adenocarcinoma.

Catenacci DV, Kang Y-K, Uronis HE, Lee K-W, Ng MC, Enzinger PC, Park SH, Gold PJ, Lacy J, Hochster HS, Oh SC, Kim YH, Marrone KA, Kelly RJ, Juergens RA, Kim JG, Alcindor T, Sym SJ, Song E-K, Chee CE, Chao Y, Kim S, Oh D-Y, Yen J, Odegaard JI, Lagow E, Li D, Sun J, Kaminker P, Moore PA, Rosales MK, Park H. Circulating Tumor DNA as a Predictive Biomarker for Clinical Outcomes With Margetuximab and Pembrolizumab in Pretreated HER2-Positive Gastric/ Gastroesophageal Adenocarcinoma. Oncology. 2023 April; 37(4):176-183.

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Low-risk meningioma: Initial outcomes from NRG Oncology/RTOG 0539

Rogers CL, Pugh SL, Vogelbaum MA, Perry A, Ashby LS, Modi JM, Alleman AM, Barani IJ, Braunstein S, Bovi JA, de Groot JF, Whitton AC, Lindhorst SM, Deb N, Shrieve DC, Shu H-K, Bloom B, Machtay M, Mishra MV, Robinson CG, Won M, Mehta MP. Low-risk meningioma: Initial outcomes from NRG Oncology/RTOG 0539. Neuro-Oncology. 2023 Jan; 25(1): 137-145

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Does the number of 6-monthly adjuvant zoledronate infusions received affect treatment efficacy for early breast cancer? A sub-study of ABCSG-12

Beltran-Bless AA, Clemons MJ, Fesl C, Greil R, Pond GR, Balic M, Vandermeer L, Bjelic-Radisic V, Singer CF, Steger GG, Helfgott R, Egle D, Sölkner L, Gampenrieder SP, Kacerovsky-Strobl S, Suppan C, Ritter M, Rinnerthaler G, Pfeiler G, Fohler H, Hlauschek D, Hilton J, Gnant M. Does the number of 6-monthly adjuvant zoledronate infusions received affect treatment efficacy for early breast cancer? A sub-study of ABCSG-12. Eur J Cancer. 2023 Feb;180:108-116.

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Optimizing Cancer Survivorship Care: Examination of Factors Associated with Transition to Primary Care

Mukherjee SD, Bainbridge D, Hillis C, Sussman J. Optimizing Cancer Survivorship Care: Examination of Factors Associated with Transition to Primary Care. Curr Oncol. 2023 Feb 24;30(3):2743-2750.

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A scoping review of natural language processing of radiology reports in breast cancer

Saha A, Burns L, Kulkarni AM. A scoping review of natural language processing of radiology reports in breast cancer. Front Oncol. 2023 Apr 12;13:1160167. d

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Emerging Biomarkers of Response to Systemic Therapies in Metastatic Clear Cell Renal Cell Carcinoma

Labaki C, Saliby RM, Bakouny Z, Saad E, Semaan K, Eid M, Lalani AK, Choueiri TK, Braun DA. Emerging Biomarkers of Response to Systemic Therapies in Metastatic Clear Cell Renal Cell Carcinoma. Hematol Oncol Clin North Am. 2023 Oct;37(5):937-942. doi: 10.1016/j.hoc.2023.05.021. Epub 2023 Jul 3. PMID: 37407357.

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An Actionable Expert-System Algorithm to Support Nurse-Led Cancer Survivorship Care: Algorithm Development Study

Pfisterer KJ, Lohani R, Janes E, Ng D, Wang D, Bryant-Lukosius D, Rendon R, Berlin A, Bender J, Brown I, Feifer A, Gotto G, Saha S, Cafazzo JA, Pham Q. An Actionable Expert-System Algorithm to Support Nurse-Led Cancer Survivorship Care: Algorithm Development Study. JMIR Cancer. 2023 Oct 4;9:e44332.

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Disease control outcomes of stereotactic body radiation therapy or moderate hypo?fractionation for prostate cancer: Real?world experience at two Canadian centers

Hu H, Anagnostopoulos G, Gouran?Savadkoohi M, Dayes I, Ishkanian A, Hallock A, et al. Disease control outcomes of stereotactic body radiation therapy or moderate hypo?fractionation for prostate cancer: Real?world experience at two Canadian centers. The Prostate . 2024 Feb;84(2):193–202.

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Ovarian cancer pathology characteristics as predictors of variant pathogenicity in BRCA1 and BRCA2

O'Mahony DG, Ramus SJ, Southey MC, Meagher NS, Hadjisavvas A, John EM, Bane A, et al. Consortium of Investigators of Modifiers of BRCA1/2; Evidence-based Network for the Interpretation of Germline Mutant Alleles Consortium. Ovarian cancer pathology characteristics as predictors of variant pathogenicity in BRCA1 and BRCA2. Br J Cancer. 2023 Jun;128(12):2283-2294. doi: 10.1038/s41416-023-02263-5. Epub 2023 Apr 19. PMID: 37076566; PMCID: PMC10241792.

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A Multi-Centre Randomized Study Comparing Two Standard of Care Chemotherapy Regimens for Lower-Risk HER2-Positive Breast Cancer

Fernandes R, Ng TL, Alzahrani MJ, Raphael J, Blanchette P, Black M, Stober C, Pond GR, Cella D, Vandermeer L, Ibrahim M, Clemons M; REaCT Investigators. A Multi-Centre Randomized Study Comparing Two Standard of Care Chemotherapy Regimens for Lower-Risk HER2-Positive Breast Cancer. Curr Oncol. 2023 Aug 4;30(8):7384-7397. doi: 10.3390/curroncol30080535. PMID: 37623016; PMCID: PMC10453132.

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Three-Year Outcomes Following Permissive Cardiotoxicity in Patients on Trastuzumab

Zhou S, Cirne F, Chow J, Zereshkian A, Bordeleau L, Dhesy-Thind S, Ellis PM, Mukherjee SD, Aghel N, Leong DP. Three-Year Outcomes Following Permissive Cardiotoxicity in Patients on Trastuzumab. Oncologist. 2023 Sep 7;28(9):e712-e722. doi: 10.1093/oncolo/oyad086. PMID: 37094996; PMCID: PMC10485282.

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Genomic Classifier Performance in Intermediate-Risk Prostate Cancer: Results From NRG Oncology/RTOG 0126 Randomized Phase 3 Trial

Spratt DE, Liu VYT, Michalski J, Davicioni E, Berlin A, Simko JP, Efstathiou JA, Tran PT, Sandler HM, Hall WA, Thompson DJS, Parliament MB, Dayes IS, Correa RJM, Robertson JM, Gore EM, Doncals DE, Vigneault E, Souhami L, Karrison TG, Feng FY. Genomic Classifier Performance in Intermediate-Risk Prostate Cancer: Results From NRG Oncology/RTOG 0126 Randomized Phase 3 Trial. Int J Radiat Oncol Biol Phys. 2023 Oct 1;117(2):370-377. doi: 10.1016/j.ijrobp.2023.04.010. Epub 2023 May 2. PMID: 37137444; PMCID: PMC10949135.

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Comparing machine learning approaches to incorporate time-varying covariates in predicting cancer survival time

Cygu S, Seow H, Dushoff J, Bolker BM. Comparing machine learning approaches to incorporate time-varying covariates in predicting cancer survival time. Sci Rep. 2023 Jan 25;13(1):1370. doi: 10.1038/s41598-023-28393-7. PMID: 36697455; PMCID: PMC9877029.

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Optimal adjuvant therapy in older (≥70 years of age) women with low-risk early-stage breast cancer

Chadha M, White J, Swain SM, Rakovitch E, Jagsi R, Whelan T, Sparano JA. Optimal adjuvant therapy in older (≥70 years of age) women with low-risk early-stage breast cancer. NPJ Breast Cancer. 2023 Dec 14;9(1):99. doi: 10.1038/s41523-023-00591-6. PMID: 38097623; PMCID: PMC10721824.

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Phase I pharmacokinetic study of single agent trametinib in patients with advanced cancer and hepatic dysfunction

Voon PJ, Chen EX, Chen HX, Lockhart AC, Sahebjam S, Kelly K, Vaishampayan UN, Subbiah V, Razak AR, Renouf DJ, Hotte SJ, Singh A, Bedard PL, Hansen AR, Ivy SP, Wang L, Stayner L-A, Siu LL, Spreafico A. Phase I pharmacokinetic study of single agent trametinib in patients with advanced cancer and hepatic dysfunction. Journal of Experimental & Clinical Cancer Research. 2022 Dec; 41(1) 51

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Disparity in public funding of systemic therapy for metastatic renal cell carcinoma within Canada

Jackson EB, Hotte SJ. Disparity in public funding of systemic therapy for metastatic renal cell carcinoma within Canada. Canadian Urological Association Journal. 2022 Nov; 16(11):E516-E522

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Exclusion of Patients With Brain Metastases in Published Phase III Clinical Trials for Advanced Breast Cancer

Sharma A, Searle K, Hasan S, Chan S, Pond G, Jerzak KJ. Exclusion of Patients With Brain Metastases in Published Phase III Clinical Trials for Advanced Breast Cancer. Clinical Breast Cancer. 2022 Oct;22(7):629-633

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An International Consensus on Actions to Improve Lung Cancer Survival: A Modified Delphi Method Among Clinical Experts in the International Cancer Benchmarking Partnership

Lynch C, Harrison S, Butler J, Baldwin DR, Dawkins P, van der Horst J, Jakobsen E, McAleese J, McWilliams A, Redmond K, Swaminath A, Finley CJ. An International Consensus on Actions to Improve Lung Cancer Survival: A Modified Delphi Method Among Clinical Experts in the International Cancer Benchmarking Partnership. Cancer Control. 2022 Jan-Dec;29:107327

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Radiation Dose, Technique and Use of Brain Radiation on Overall Survival in Patients with Limited-Stage Small Cell Lung Cancer

Palchik S, Pond G, Wu CHD, Wright J, Tsakiridis T, Swaminath A. Radiation Dose, Technique and Use of Brain Radiation on Overall Survival in Patients with Limited-Stage Small Cell Lung Cancer. International Journal of Radiation Oncology. 2022 Nov;114(3);e411

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Long-Term Outcomes of SABR to Primary Renal Cell Carcinoma: A Multicenter Analysis from IROCK (International Radiosurgery Oncology Consortium for Kidney)

Siva S, Correa RJM, Ali M, Muacevic A, Ponsky L, Ellis RJ, Lo SS, Onishi H, Swaminath A, McLaughlin M, Morgan SC, Cury F, Teh BS, Mahadevan A, Kaplan ID, Chu W, Hannan R, Staehler M, Warner A, Louie AV. Long-Term Outcomes of SABR to Primary Renal Cell Carcinoma: A Multicenter Analysis from IROCK (International Radiosurgery Oncology Consortium for Kidney). International Journal of Radiation Oncology. 2022 Nov: 14(3): s177

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The impact of operative approach for obese colorectal cancer patients: analysis of the National Inpatient Sample 2015–2019

Logie K, McKechnie T, Talwar G, Lee Y, Parpia S, Amin N, Doumouras A, Hong D, Eskicioglu C. The impact of operative approach for obese colorectal cancer patients: analysis of the National Inpatient Sample 2015-2019. Colorectal Dis. 2024 Jan;26(1):34-44. doi: 10.1111/codi.16808. Epub 2023 Nov 23. PMID: 37994236.

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Phase I Dose-Escalation Study of the Safety and Pharmacokinetics of AGS15E Monotherapy in Patients with Metastatic Urothelial Carcinoma

Petrylak DP, Eigl BJ, George S, Heath EI, Hotte SJ, Chism DD, Nabell LM, Picus J, Cheng SY, Appleman LJ, Sonpavde GP, Morgans AK, Pourhosseini P, Wu R, Standley L, Croitoru R, Yu EY. Phase I Dose-Escalation Study of the Safety and Pharmacokinetics of AGS15E Monotherapy in Patients with Metastatic Urothelial Carcinoma. Clin Cancer Res. 2024 Jan 5;30(1):63-73. doi: 10.1158/1078-0432.CCR-22-3627. PMID: 37861407; PMCID: PMC10767306.

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Evaluation of the implementation of advanced practice nursing roles in France: A multiple case study

Schwingrouber, J., Bryant-Lukosius, D., Kilpatrick, K., Mayen, S., & Colson, S. (2024). Evaluation of the implementation of advanced practice nursing roles in France: A multiple case study. Journal of advanced nursing, 80(3), 977–992. https://doi.org/10.1111/jan.15840

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A Canadian survey of perceptions and practices related to ordering of blood tests in the intensive care unit

Rahman, M. O., Charbonney, E., Vaisler, R., Khalifa, A., Alhazzani, W., Gossack-Keenan, K., Garland, A., Karachi, T., Duan, E., Bagshaw, S. M., Meade, M. O., Hillis, C., Kavsak, P., Born, K., Mbuagbaw, L., Siegal, D., Millen, T., et al. Rochwerg, B. (2024). A Canadian survey of perceptions and practices related to ordering of blood tests in the intensive care unit. Enquête canadienne sur les perceptions et pratiques liées à la prescription de tests sanguins aux soins intensifs. Canadian journal of anaesthesia = Journal canadien d'anesthesie, 10.1007/s12630-024-02745-x. Advance online publication. https://doi.org/10.1007/s12630-024-02745-x

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Editorial for “Intra‐ and Peri‐tumoral Radiomics Based on Dynamic Contrast Enhanced‐MRI to Identify Lymph Node Metastasis and Prognosis in Intrahepatic Cholangiocarcinoma”

Saha, A., Almalki, Y. E., & van der Pol, C. B. (2024). Editorial for "Intra- and Peri-tumoral Radiomics Based on Dynamic Contrast Enhanced-MRI to Identify Lymph Node Metastasis and Prognosis in Intrahepatic Cholangiocarcinoma". Journal of magnetic resonance imaging : JMRI, 10.1002/jmri.29391. Advance online publication. https://doi.org/10.1002/jmri.29391

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Time to full weight-bearing with the use of a calcium sulfate-calcium phosphate bone substitute as a bone void filler following extended curettage in the treatment of primary benign bone tumours.

Gyemi L, Selznick A, Petrisor B, Ghert M. Time to full weight-bearing with the use of a calcium sulfate-calcium phosphate bone substitute as a bone void filler following extended curettage in the treatment of primary benign bone tumours. J Orthop Surg (Hong Kong). 2024 May-Aug;32(2):10225536241254200. doi: 10.1177/10225536241254200. PMID: 38733211.

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Socioeconomic marginalization and health outcomes in newly diagnosed multiple myeloma: A population-based cohort study

Visram A, Seow H, Fiala MA, Gayowsky A, Cheung M, Davies G, Pond GR, Mian H. American Journal of Hematology. Am J Hematol. 2023;1–3.

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Impact of Second Primary Malignancy Post-Autologous Transplantation on Outcomes of Multiple Myeloma: A CIBMTR Analysis

Ragon BK, Shah MV, D’Souza A, Estrada-Merly N, Gowda L, George G, de Lima M, Hashmi S, Kharfan-Dabaja MA, Majhail NS, Banerjee R, Saad A, Hildebrandt GC, Mian H, Abid MB, Battiwalla M, Lekakis LJ, Patel SS, Murthy HS, Nieto Y, Strouse C, Badawy SM, Hadidi SA, Dholaria B, Aljurf M, Vesole DH, Lee CH, Pawarode A, Gergis U, Miller KC, Holmberg LA, Afrough A, Solh M, Munshi PN, Nishihori T, Anderson LD, Wirk B, Kaur G, Qazilbash MH, Shah N, Kumar SK, Usmani SZ. Impact of Second Primary Malignancy Post-Autologous Transplantation on Outcomes of Multiple Myeloma: A CIBMTR Analysis. Blood Advances. 2023 June; 7(12) 2746-2757.

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Mepitel Film for the Prevention of Acute Radiation Dermatitis in Breast Cancer: A Randomized Multi-Centre Open-Label Phase 3 Trial

Behroozian T, Milton L, Karam I, Zhang L, Ding K, Lou J, Gallant F, Rakovitch E, Tran W, Soliman H, Leung E, Vesprini D, Szumacher E, Chen H, Donovan E, Lam J, Spadafora S, Wronski M, Lavoie C, Walde N, Lam E, Wong G, McKenzie E, Ariello K, Kennedy S, Shariati S, Carothers K, Gonzales G, Kaga Y, Chow E. Mepitel Film for the Prevention of Acute Radiation Dermatitis in Breast Cancer: A Randomized Multi-Centre Open-Label Phase 3 Trial. Journal of Medical Imaging and Radiation. 2023 April; 54(1) :2-3.

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Cardiovascular Outcomes During Index Hospitalization in Children with Kawasaki Disease in Ontario, Canada

Robinson C, Schlorff M, Chanchlani R, Gayowsky A, Darling E, Mondal T, Seow H, Batthish M. Cardiovascular Outcomes During Index Hospitalization in Children with Kawasaki Disease in Ontario, Canada. Pediatric Cardiology. 2023 Mar;44(3):681-688.

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Durvalumab Plus Olaparib in Previously Untreated, Platinum-Ineligible Patients With Metastatic Urothelial Carcinoma: A Multicenter, Randomized, Phase II Trial (BAYOU)

Rosenberg JE, Park SH, Kozlov V, Dao TV, Castellano D, Li JR, Mukherjee SD, Howells K, Dry H, Lanasa MC, Stewart R, Bajorin DF. Durvalumab Plus Olaparib in Previously Untreated, Platinum-Ineligible Patients With Metastatic Urothelial Carcinoma: A Multicenter, Randomized, Phase II Trial (BAYOU). J Clin Oncol. 2023 Jan 1;41(1):43-53.

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A Competition, Benchmark, Code, and Data for Using Artificial Intelligence to Detect Lesions in Digital Breast Tomosynthesis

Konz N, Buda M, Gu H, Saha A, Yang J, Chledowski J, Park J, Witowski J, Geras KJ, Shoshan Y, Gilboa-Solomon F, Khapun D, Ratner V, Barkan E, Ozery-Flato M, Martí R, Omigbodun A, Marasinou C, Nakhaei N, Hsu W, Sahu P, Hossain MB, Lee J, Santos C, Przelaskowski A, Kalpathy-Cramer J, Bearce B, Cha K, Farahani K, Petrick N, Hadjiiski L, Drukker K, Armato SG 3rd, Mazurowski MA. A Competition, Benchmark, Code, and Data for Using Artificial Intelligence to Detect Lesions in Digital Breast Tomosynthesis. JAMA Netw Open. 2023 Feb 1;6(2):e230524.

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Location of death among children with life-threatening conditions: a national population-based observational study using the Canadian Vital Statistics Database (2008–2014)

Widger K, Brennenstuhl S, Tanuseputro P, Nelson KE, Rapoport A, Seow H, Siden H, Vadeboncoeur C, Gupta S. Location of death among children with life-threatening conditions: a national population-based observational study using the Canadian Vital Statistics Database (2008-2014). CMAJ Open. 2023 Apr 4;11(2):E298-E304.

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A pilot study of adherence to lenalidomide among older patients with multiple myeloma

Silberstein AE, Fiala MA, Loh KP, Cordner T, Mian H, Wildes TM. A pilot study of adherence to lenalidomide among older patients with multiple myeloma. J Geriatr Oncol. 2023 Sep;14(7):101560.

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A history of bariatric surgery before surgery for colorectal cancer may improve short-term postoperative outcomes: Analysis of the national inpatient sample 2015–2019

McKechnie T, Lee Y, Hong D, Dionne J, Doumouras A, Parpia S, Bhandari M, Eskicioglu C. A history of bariatric surgery before surgery for colorectal cancer may improve short-term postoperative outcomes: Analysis of the national inpatient sample 2015–2019. Surgery. 20203 Nov; 174(5): 1168-1174

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What’s New in Musculoskeletal Tumor Surgery.

Gazendam A, Ghert M. What's New in Musculoskeletal Tumor Surgery. J Bone Joint Surg Am. 2023 Dec 20;105(24):1929-1936.

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The evolution of immune checkpoint inhibitor combinations in advanced hepatocellular carcinoma – A systematic review

Meyers BM, Knox JJ, Liu DM, McLeod D, Ramjeesingh R, Tam VC, Lim HJ. The evolution of immune checkpoint inhibitor combinations in advanced hepatocellular carcinoma - A systematic review. Cancer Treat Rev. 2023 Jul;118:102584. doi: 10.1016/j.ctrv.2023.102584. Epub 2023 May 27. PMID: 37336142.

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Trainee Evaluations of Preparedness for Clinical Trials in Medical Oncology—A National Questionnaire

Febbraro M, Kazemi G, Juergens R, Pond GR. Trainee Evaluations of Preparedness for Clinical Trials in Medical Oncology-A National Questionnaire. Curr Oncol. 2023 Aug 15;30(8):7627-7637. doi: 10.3390/curroncol30080553. PMID: 37623034; PMCID: PMC10453465.

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Combination of an ACLY inhibitor with a GLP-1R agonist exerts additive benefits on nonalcoholic steatohepatitis and hepatic fibrosis in mice

Desjardins EM, Wu J, Lavoie DCT, Ahmadi E, Townsend LK, Morrow MR, Wang D, Tsakiridis EE, Batchuluun B, Fayyazi R, Kwiecien JM, Tsakiridis T, Lally JSV, Paré G, Pinkosky SL, Steinberg GR. Combination of an ACLY inhibitor with a GLP-1R agonist exerts additive benefits on nonalcoholic steatohepatitis and hepatic fibrosis in mice. Cell Rep Med. 2023 Sep 19;4(9):101193. doi: 10.1016/j.xcrm.2023.101193. PMID: 37729871; PMCID: PMC10518624.

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5-Year Renal Function Outcomes after SABR for Primary Renal Cell Carcinoma: A Report from the International Radiosurgery Oncology Consortium of the Kidney (IROCK)

Tan, V. S., Correa, R. J. M., Warner, A., Ali, M., Muacevic, A., Ponsky, L., Ellis, R. J., Lo, S. S., Onishi, H., Swaminath, A., et al. (2023). 5-year renal function outcomes after SABR for primary renal cell carcinoma: A report from the International Radiosurgery Oncology Consortium of the kidney (IROCK). International Journal of Radiation Oncology*Biology*Physics, 117(2). https://doi.org/10.1016/j.ijrobp.2023.06.405

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Construct validity of advanced practice nurse core competence scale: an exploratory factor analysis

Chair SY, Wong FKY, Bryant-Lukosius D, Liu T, Jokiniemi K. Construct validity of advanced practice nurse core competence scale: an exploratory factor analysis. BMC Nurs. 2023 Mar 2;22(1):57. doi: 10.1186/s12912-023-01203-1. PMID: 36864420; PMCID: PMC9979114.

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Real world data on outcomes of anti-CD38 antibody treated, including triple class refractory, patients with multiple myeloma: a multi-institutional report from the Canadian Myeloma Research Group (CMRG) Database

Visram A, De La Torre A, White D, Su J, Masih-Khan E, Chu M, Jimenez-Zepeda V, McCurdy A, LeBlanc R, Song K, Mian H, et al. Real world data on outcomes of anti-CD38 antibody treated, including triple class refractory, patients with multiple myeloma: a multi-institutional report from the Canadian Myeloma Research Group (CMRG) Database. Blood Cancer J. 2023 Dec 8;13(1):181. doi: 10.1038/s41408-023-00946-z. PMID: 38065967; PMCID: PMC10709576.

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Salvage radiotherapy following HiFU: An institutional series and literature review

Mesci A, Gouran?Savadkoohi M, Ribeiro D, Dayes I, Lukka H, Schnarr K, Quan K, Goldberg M, Hallock A, Tsakiridis T. Salvage radiotherapy following HiFU: An institutional series and literature review. Journal of Medical Imaging and Radiation. 2022 Sept; 6(6) 847-852

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The Cost Effectiveness of Axicabtagene Ciloleucel Versus Best Supportive Care in the Treatment of Adult Patients with Relapsed or Refractory Large B-Cell Lymphoma (LBCL) After Two or More Lines of Systemic Therapy in Canada

Hillis C, Vicente C, Ball G. The Cost Effectiveness of Axicabtagene Ciloleucel Versus Best Supportive Care in the Treatment of Adult Patients with Relapsed or Refractory Large B-Cell Lymphoma (LBCL) After Two or More Lines of Systemic Therapy in Canada. PharmacoEconomics. 2022 Sep;40(9):917-928

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Study protocol for assessing knowledge, attitudes and belief towards HPV vaccination of parents with children aged 9–14 years in rural communities of North West Cameroon: a qualitative study

Elit L, Ngalla C, Afugchwi GM, Tum E, Fokom-Domgue J, Nouvet E. Study protocol for assessing knowledge, attitudes and belief towards HPV vaccination of parents with children aged 9–14 years in rural communities of North West Cameroon: a qualitative study. BMJ Open. 2022 Aug 24;12(8):e062556.

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Association of Long-term Outcomes With Stereotactic Radiosurgery vs Whole-Brain Radiotherapy for Resected Brain Metastasis

Palmer JD, Klamer BG, Ballman KV, Brown PD, Cerhan JH, Anderson SK, Carrero XW, Whitton AC, Greenspoon J, Parney IF, Laack NNI, Ashman JB, Bahary JP, Hadjipanayis CG, Urbanic JJ, Barker FG 2nd, Farace E, Khuntia D, Giannini C, Buckner JC, Galanis E, Roberge D. Association of Long-term Outcomes With Stereotactic Radiosurgery vs Whole-Brain Radiotherapy for Resected Brain Metastasis: A Secondary Analysis of The N107C/CEC.3 (Alliance for Clinical Trials in Oncology/Canadian Cancer Trials Group) Randomized Clinical Trial. JAMA Oncol. 2022 Dec 1;8(12):1809-1815.

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Patterns of care for non?metastatic castration?resistant prostate cancer: A population?based study

Malone S, Wallis CJD, Lee-Ying R, Basappa NS, Cagiannos I, Hamilton RJ, Fernandes R, Ferrario C, Gotto GT, Morgan SC, Morash C, Niazi T, Noonan KL, Rendon R, Hotte SJ, Saad F, Zardan A, Osborne B, Chan KFY, Shayegan B. Patterns of care for non-metastatic castration-resistant prostate cancer: A population-based study. BJUI Compass. 2022 May 18;3(5):383-391.

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EP04.02-002 International Consensus on Actions to Improve Lung Cancer Survival: Delphi Method in the International Cancer Benchmarking Partnership

EP04.02-002 International Consensus on Actions to Improve Lung Cancer Survival: Delphi Method in the International Cancer Benchmarking Partnership. Journal of Thoracic Oncology. 2022 Sep: 17(9): s260-s261

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Molecular Testing in Non–Small-Cell Lung Cancer: A Call to Action

Sathiyapalan A, Ellis PM. Molecular Testing in Non-Small-Cell Lung Cancer: A Call to Action. JCO Oncol Pract. 2024 Jan;20(1):7-9. doi: 10.1200/OP.23.00669. Epub 2023 Nov 30. PMID: 38033274.

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Meta-Analysis of STereotactic body radiothERapy in non-spine BONE metastaseS (MASTER-BONES).

Moraes FY, Gouveia AG, Marta GN, da Silva MF, Hamamura AC, Tsakiridis T, Yan M, Viani GA. Meta-Analysis of STereotactic body radiothERapy in non-spine BONE metastaseS (MASTER-BONES). Int J Radiat Oncol Biol Phys. 2024 Jan 18:S0360-3016(24)00002-6. doi: 10.1016/j.ijrobp.2023.12.045. Epub ahead of print. PMID: 38244875.

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Fragility of Statistically Significant Outcomes in Colonic Diverticular Disease Randomized Trials: A Systematic Review

McKechnie, T., Yang, S., Wu, K., Sharma, S., Lee, Y., Park, L. J., Passos, E. M., Doumouras, A. G., Hong, D., Parpia, S., Bhandari, M., & Eskicioglu, C. (2024). Fragility of Statistically Significant Outcomes in Colonic Diverticular Disease Randomized Trials: A Systematic Review. Diseases of the colon and rectum, 67(3), 414–426. https://doi.org/10.1097/DCR.0000000000003014

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The successful management of acute promyelocytic leukemia during pregnancy: a case report

Salter, B., Radford, J. M., Berg, T., & Leber, B. (2024). The successful management of acute promyelocytic leukemia during pregnancy: a case report. Leukemia & lymphoma, 65(4), 526–529. https://doi.org/10.1080/10428194.2023.2295786

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Validation of the prognostic performance of Breast Cancer Index (BCI) in hormone receptor-positive (HR+) postmenopausal breast cancer patients in the TEAM trial

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Tu1414 FACTORS ASSOCIATED WITH PHYSICAL SYMPTOM BURDEN AMONG PATIENTS WITH PANCREATIC ADENOCARCINOMA

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Development and Validation of an Indicator for Oncofertility Care in Ontario, Canada, for Adolescents and Young Adults with Cancer

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Heterogeneity across outcomes reported in clinical trials for older adults with depression: a systematic survey

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Detection of macrotroponin in patients receiving treatment for breast cancer

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Real?world data on lenalidomide dosing and outcomes in patients newly diagnosed with multiple myeloma: Results from the Canadian Myeloma Research Group Database

Mian H, LeBlanc R, Louzada M, Masih?Khan E, McCurdy A, Venner CP, Stakiw J, Kardjadj M, Jimenez?Zepeda VH, Sebag M, White D, Aslam M, Song K, Reiman A, Kotb R, Gul E, Reece D. Real?world data on lenalidomide dosing and outcomes in patients newly diagnosed with multiple myeloma: Results from the Canadian Myeloma Research Group Database. Cancer Medicine. 2023 Feb;12(4):4357-4362..

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The risks of cancer in older women with BRCA pathogenic variants: How far have we come?

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Mutant p53 sustains serine-glycine synthesis and essential amino acids intake promoting breast cancer growth

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Canadian Consensus Recommendations on the Management of Extensive-Stage Small-Cell Lung Cancer

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Multivariate analysis of breast tissue using optical parameters extracted from a combined time-resolved fluorescence and diffuse reflectance system for tumor margin detection

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1893P Immune-related adverse events from contemporary first-line combination therapies in metastatic renal cell carcinoma: Results from the IMDC

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Re-examining content validity of the BREAST-Q more than a decade later to determine relevance and comprehensiveness

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Immunomodulatory drugs have divergent effects on humoral and cellular immune responses to SARS-CoV-2 vaccination in people living with rheumatoid arthritis

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Outcomes of daratumumab in the treatment of multiple myeloma: A retrospective cohort study from the Canadian Myeloma Research Group Database

LeBlanc R, Mian H, Reece D, Masih?Khan E, Kardjadj M, Jimenez?Zepeda VH, McCurdy A, Song K, Sebag M, Louzada M, White D, Stakiw J, Kotb R, Reiman A, Aslam M, Gul E, Venner CP. Outcomes of daratumumab in the treatment of multiple myeloma: A retrospective cohort study from the Canadian Myeloma Research Group Database. British Journal of Hematology. 2022 July; 198(1) 93-102

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Bilateral Oophorectomy and the Risk of Breast Cancer in BRCA1 Mutation Carriers: A Reappraisal.

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A randomised controlled trial evaluating two cognitive rehabilitation approaches for cancer survivors with perceived cognitive impairment

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Cytomegalovirus Seropositivity in Older Adults Changes the T Cell Repertoire but Does Not Prevent Antibody or Cellular Responses to SARS-CoV-2 Vaccination.

Breznik JA, Huynh A, Zhang A, Bilaver L, Bhakta H, Stacey HD, Ang JC, Bramson JL, Nazy I, Miller MS, Denburg J, Costa AP, Bowdish DME; other members of the COVID-in-LTC Investigator Group. Cytomegalovirus Seropositivity in Older Adults Changes the T Cell Repertoire but Does Not Prevent Antibody or Cellular Responses to SARS-CoV-2 Vaccination. J Immunol. 2022 Nov 15;209(10):1892-1905. doi: 10.4049/jimmunol.2200369. PMID: 36426948; PMCID: PMC9666329.

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Future Leadership: Advanced Practice Nursing

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Stereotactic Radiation for Ultra-Central Non-Small Cell Lung Cancer: A Safety and Efficacy Trial (SUNSET)

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Factors Associated With Adolescent and Young Adult Females Attending a Fertility Consultation Within 30 Days of a Cancer Diagnosis in Ontario, Canada

Rae CS, Costa A, Seow H, Barr RD. Factors Associated With Adolescent and Young Adult Females Attending a Fertility Consultation Within 30 Days of a Cancer Diagnosis in Ontario, Canada. J Adolesc Young Adult Oncol. 2024 Feb;13(1):189-196. doi: 10.1089/jayao.2023.0019. Epub 2023 Jun 6. PMID: 37279019.

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Partial Breast Irradiation for Patients With Early-Stage Invasive Breast Cancer or Ductal Carcinoma In Situ: An ASTRO Clinical Practice Guideline

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Addressing controversial areas in the management of advanced prostate cancer in Canada : Areas of consensus and controversy from the third Canadian consensus forum

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Identification of cells of leukemic stem cell origin with non-canonical regenerative properties

Hollands, C. G., Boyd, A. L., Zhao, X., Reid, J. C., Henly, C., ElRafie, A., Boylan, D., Broder, E., Kalau, O., Johnson, P., Mark, A., McNicol, J., Xenocostas, A., Berg, T., Foley, R., Trus, M., Leber, B., Garcia-Horton, A., Campbell, C., & Bhatia, M. (2024). Identification of cells of leukemic stem cell origin with non-canonical regenerative properties. Cell reports. Medicine, 5(4), 101485. https://doi.org/10.1016/j.xcrm.2024.101485

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Building Palliative Care Capacity for Generalist Providers in the Community: Results From the Capaciti Pilot Education Program

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Five-Year Patient-Reported Outcomes in NRG Oncology RTOG 0938, Evaluating Two Ultrahypofractionated Regimens for Prostate Cancer

Lukka HR, Deshmukh S, Bruner DW, Bahary J-P, Lawton CAF, Efstathiou JA, Kudchadker RJ, Ponsky LE, Seaward SA, Dayes IS, Gopaul DD, Michalski JM, Delouya G, Kaplan ID, Horwitz EM, Roach M, Feng FY, Pugh SL, Sandler HM, Kachnic LA. Five-Year Patient-Reported Outcomes in NRG Oncology RTOG 0938, Evaluating Two Ultrahypofractionated Regimens for Prostate Cancer. International Journal of Radiation Oncology. 2023 July; 116(4) 770-778.

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Impact of 18F-Labeled Fluorodeoxyglucose Positron Emission Tomography-Computed Tomography Versus Conventional Staging in Patients With Locally Advanced Breast Cancer.

Dayes IS, Metser U, Hodgson N, Parpia S, Eisen AF, George R, Blanchette P, Cil TD, Arnaout A, Chan A, Levine MN. Impact of 18F-Labeled Fluorodeoxyglucose Positron Emission Tomography-Computed Tomography Versus Conventional Staging in Patients With Locally Advanced Breast Cancer. Journal of Clinical Oncology 2023 May. 41(23).

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A Meta-Analysis of Trials of Partial Breast Irradiation

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The burden of red blood cell transfusions in patients with lower-risk myelodysplastic syndromes and ring sideroblasts: an analysis of the prospective MDS-CAN registry

Buckstein R, Chodirker L, Yee KWL, Geddes M, Leitch HA, Christou G, Banerji V, Leber B, Khalaf D, St-Hilaire E, Finn N, Nevill T, Keating MM, Storring J, Parmentier A, Thambipillai A, Tang D, Westcott C, Cameron C, Spin P. The burden of red blood cell transfusions in patients with lower-risk myelodysplastic syndromes and ring sideroblasts: an analysis of the prospective MDS-CAN registry. Leuk Lymphoma. 2023 Mar;64(3):651-661.

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Outcome measures in palliative care training interventions: a systematic review of trial-based studies

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Prospective ctDNA genotyping for treatment selection in metastatic castration-resistant prostate cancer (mCRPC): The Canadian Cancer Trials Group phase II PC-BETS umbrella study.

Kwan EM, Rushton MK, Tu W, Hotte SJ, Mukherjee SD, Ong M, Kolinsky MP, Hamilou Z, Winquist E, Ferrario C, Macfarlane RJ, Saad F, Salim M, Jiang DM, Tu D, Hutchenreuther J, Annala M, Seymour L, Chi KN, Wyatt AW. Prospective ctDNA genotyping for treatment selection in metastatic castration-resistant prostate cancer (mCRPC): The Canadian Cancer Trials Group phase II PC-BETS umbrella study. Journal of Clinical Oncology. 2023 Oct: 41(6) 2:218

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The CCTG PA.7 phase II trial of gemcitabine and nab-paclitaxel with or without durvalumab and tremelimumab as initial therapy in metastatic pancreatic ductal adenocarcinoma

Renouf DJ, Loree JM, Knox JJ, Topham JT, Kavan P, Jonker D, Welch S, Couture F, Lemay F, Tehfe M, Harb M, Aucoin N, Ko Y-J, Tang PA, Ramjeesingh R, Meyers BM, Kim CA, Du P, Jia S, Schaeffer DF, Gill S, Tu D, O’Callaghan CJ. The CCTG PA.7 phase II trial of gemcitabine and nab-paclitaxel with or without durvalumab and tremelimumab as initial therapy in metastatic pancreatic ductal adenocarcinoma. Nature Communications. 2022 Aug:

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Long-Term Toxicity in Patients Receiving Radiotherapy for Ultracentral Stage I Non-Small Cell Lung Cancer – A Secondary Analysis of the LUSTRE Randomized Trial

Wu CHD, Wierzbicki M, Parpia S, Kundapur V, Bujold A, Filion EJ, et al. Long-term toxicity in patients receiving radiotherapy for ultracentral stage i non-small cell lung cancer – a secondary analysis of the lustre randomized trial. International Journal of Radiation Oncology. 2023 Oct 1 ;117(2) s171

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Omitting Radiotherapy in Luminal A Breast Cancer

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Lorlatinib Effectiveness and Quality-of-Life in Patients with ALK-Positive NSCLC Who Had Failed Second-Generation ALK Inhibitors: Canadian Real-World Experience

Rupp M, Fanton-Aita F, Snow S, Wheatley-Price P, Melosky B, Juergens RA, Chu Q, Blais N, Banerji S, Ng R, Khoudigian S, Sharma A, On PV, Liu G. Lorlatinib Effectiveness and Quality-of-Life in Patients with ALK-Positive NSCLC Who Had Failed Second-Generation ALK Inhibitors: Canadian Real-World Experience. Curr Oncol. 2023 Jul 8;30(7):6559-6574. doi: 10.3390/curroncol30070481. PMID: 37504341; PMCID: PMC10377946.

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Perceptions of Cancer in Parents of Adolescent Daughters in Northwest Cameroon

Elit L, Tum EM, Ngalla C, Fungchwi GM, Fokom Domgue J, Nouvet E. Perceptions of Cancer in Parents of Adolescent Daughters in Northwest Cameroon. Curr Oncol. 2023 Jul 25;30(8):7167-7177. doi: 10.3390/curroncol30080519. PMID: 37623000; PMCID: PMC10453201.

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Emerging Biomarkers of Response to Systemic Therapies in Metastatic Clear Cell Renal Cell Carcinoma

Labaki C, Saliby RM, Bakouny Z, Saad E, Semaan K, Eid M, Lalani AK, Choueiri TK, Braun DA. Emerging Biomarkers of Response to Systemic Therapies in Metastatic Clear Cell Renal Cell Carcinoma. Hematol Oncol Clin North Am. 2023 Oct;37(5):937-942. doi: 10.1016/j.hoc.2023.05.021. Epub 2023 Jul 3. PMID: 37407357.

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Protocol for a living evidence synthesis on variants of concern and COVID-19 vaccine effectiveness

Shaver N, Katz M, Darko Asamoah G, Linkins LA, Abdelkader W, Beck A, Bennett A, Hughes SE, Smith M, Begin M, Coyle D, Piggott T, Kagina BM, Welch V, Colijn C, Earn DJD, El Emam K, Heffernan J, O'Brien SF, Wilson K, Collins E, Navarro T, Beyene J, Boutron I, Bowdish D, Cooper C, Costa A, Curran J, Griffith L, Hsu A, Grimshaw J, Langlois MA, Li X, Pham-Huy A, Raina P, Rubini M, Thabane L, Wang H, Xu L, Brouwers M, Horsley T, Lavis J, Iorio A, Little J. Protocol for a living evidence synthesis on variants of concern and COVID-19 vaccine effectiveness. Vaccine. 2023 Oct 13;41(43):6411-6418. doi: 10.1016/j.vaccine.2023.09.012. Epub 2023 Sep 16. PMID: 37718186.

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A phase 2 study of stereotactic body radiation therapy for squamous cell carcinoma of the head and neck (SHINE): a single arm clinical trial protocol

Lee J, Nguyen NT, Wright J, Yeung KD, Sagar S, Kim DH, Ostapiak O, Doerwald-Munoz L, Whelan T. A phase 2 study of stereotactic body radiation therapy for squamous cell carcinoma of the head and neck (SHINE): a single arm clinical trial protocol. BMC Cancer. 2023 Apr 26;23(1):379. doi: 10.1186/s12885-023-10807-4. PMID: 37098494; PMCID: PMC10131380.

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Derivation of the Falls Decision Rule to exclude intracranial bleeding without head CT in older adults who have fallen

Wit, Kerstin & Mercuri, Mathew & Clayton, Natasha & Mercier, Eric & Morris, Judy & Jeanmonod, Rebecca & Eagles, Debra & Varner, C. & Barbic, David & Buchanan, Ian & Ali, Mariyam & Kagoma, Yoan & Shoamanesh, Ashkan & Engels, Paul & Sharma, Sunjay & Worster, Andrew & Mcleod, Shelley & Emond, Marcel & Stiell, Ian & Parpia, Sameer. (2023). Derivation of the Falls Decision Rule to exclude intracranial bleeding without head CT in older adults who have fallen. Canadian Medical Association Journal. 195. E1614-E1621. 10.1503/cmaj.230634.

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Survival and Outcomes of Newly Diagnosed Multiple Myeloma Patients Stratified by Transplant Status 2007-2018: Retrospective Analysis from the Canadian Myeloma Research Group Database

Mian H, Reece D, Masih-Khan E, McCurdy A, Kardjadj M, Jimenez-Zepeda VH, Song K, Louzada M, LeBlanc R, Sebag M, White D, Stakiw J, Reiman A, Kotb R, Aslam M, Gul E, Venner CP. Survival and Outcomes of Newly Diagnosed Multiple Myeloma Patients Stratified by Transplant Status 2007-2018: Retrospective Analysis from the Canadian Myeloma Research Group Database. Clinical Lymphoma Myeloma & Leukemia. 2022 Aug; 22(8) 608-617

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Emerging Biomarker-Guided Therapies in Prostate Cancer

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What do hematology residents know about caring for older adults with cancer? A national survey of Canadian hematology residents’ knowledge and interests

David V, Hsu T, Mithoowani S, Fraser G, Mian H. What do hematology residents know about caring for older adults with cancer? A national survey of Canadian hematology residents' knowledge and interests. Journal of Geriatric Oncology. 2022 Nov;13(8):1236-1240.

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A phase II trial of GSK2256098 and trametinib in patients with advanced pancreatic ductal adenocarcinoma

Aung KL, McWhirter E, Welch S, Wang L, Lovell S, Stayner LA, Ali S, Malpage A, Makepeace B, Ramachandran M, Jang GH, Gallinger S, Zhang T, Stockley TL, Fischer SE, Dhani N, Hedley D, Knox JJ, Siu LL, Goodwin R, Bedard PL. A phase II trial of GSK2256098 and trametinib in patients with advanced pancreatic ductal adenocarcinoma. J Gastrointest Oncol. 2022 Dec;13(6):3216-3226.

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Choosing which in-hospital laboratory tests to target for intervention: a scoping review

Podolsky E, Hudek N, McCudden C, Presseau J, Yanikomeroglu S, Brouwers M, Brehaut JC. Choosing which in-hospital laboratory tests to target for intervention: a scoping review. Clin Chem Lab Med. 2022 Nov 22;61(3):388-401. doi: 10.1515/cclm-2022-0910. PMID: 36410390; PMCID: PMC9876731.

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Dosing, efficacy and safety of lenvatinb in the real?world treatment of hepatocellular carcinoma: Results from a Canadian database

Amaro CP, Allen MJ, Knox JJ, Tsang ES, Lim HJ, Lee?Ying RM, Chan KW, Qian J, Meyers BM, Thawer A, Al?Saadi SMS, Hsu T, Ramjeesingh R, Karachiwala H, Abedin T, Tam VC. Dosing, efficacy and safety of lenvatinb in the real?world treatment of hepatocellular carcinoma: Results from a Canadian database. Liver Cancer International. 2023 Jun:3(3): 119-127

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LUMINA: Using molecular biomarkers to guide decision making for breast radiotherapy

Whelan TJ, Fyles A, Parpia S, Nielsen T, Levine MN. LUMINA: Using molecular biomarkers to guide decision making for breast radiotherapy. Radiother Oncol. 2024 Jan;190:110074. doi: 10.1016/j.radonc.2023.110074. Epub 2023 Dec 30. PMID: 38163484.

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Education modalities for serious illness communication training: A scoping review on the impact on clinician behavior and patient outcomes

Lavecchia M, Myers J, Bainbridge D, Incardona N, Levine O, Steinberg L, Schep D, Vautour J, Kumar SJ, Seow H. Education modalities for serious illness communication training: A scoping review on the impact on clinician behavior and patient outcomes. Palliat Med. 2024 Feb;38(2):170-183. doi: 10.1177/02692163231186180. Epub 2023 Jul 9. PMID: 37424275; PMCID: PMC10865772.

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Preclinical characterization and clinical trial of CFI-400945, a polo-like kinase 4 inhibitor, in patients with relapsed/refractory acute myeloid leukemia and higher-risk myelodysplastic neoplasms

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The COVID-19 pandemic and its effects on follow-up of patients with early breast cancer: A patient survey

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Prevalence of geriatric impairments and frailty categorization among real-world patients with multiple myeloma: a prospective cohort study (MFRAIL)

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Identifying Very-Low-Risk Patients for Future Myocardial Infarction or Death

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Clinical consensus statement: Establishing the roles of locoregional and systemic therapies for the treatment of intermediate-stage hepatocellular carcinoma in Canada

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Factors Associated With Adolescent and Young Adult Females Attending a Fertility Consultation Within 30 Days of a Cancer Diagnosis in Ontario, Canada

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Evaluation of the prevalence of the most common psychiatric disorders in patients with type 2 diabetes mellitus using the patient health questionnaire: results of the cross-sectional “DIA2PSI” study

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Web-Based Asynchronous Tool to Facilitate Communication Between Primary Care Providers and Cancer Specialists: Pragmatic Randomized Controlled Trial

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Recent Advances in Optimizing Radiation Therapy Decisions in Early Invasive Breast Cancer

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Adjuvant therapy for renal cell carcinoma: 2023 Canadian Kidney Cancer Forum consensus statement

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Spindle cell oncocytoma reclassified from amelanotic melanocytoma of the sellar region.

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Treatment Modalities to Manage Hepatocellular Carcinoma Patients with Portal Vein Thrombus: A Systematic Review and Meta-Analysis

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Protocol for a longitudinal cohort study of Lyme disease with physical, mental and immunological assessment

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Canadian Consensus Recommendations on the Management of KRAS G12C-Mutated NSCLC

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Chronic immune-related adverse events in patients with cancer receiving immune checkpoint inhibitors: a systematic review

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Optimizing Treatment Selection in Advanced Renal Cell Carcinoma via IMDC Risk Group Stratification

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Characteristics of post hoc subgroup analyses of oncology clinical trials: a systematic review

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Characterizing the Palliative Care Physician Workforce: A Retrospective Cross-Sectional Study With Population-Based Data in Ontario, Canada

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Safety and efficacy of immune checkpoint inhibitors in advanced penile cancer: report from the Global Society of Rare Genitourinary Tumors

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Important questions for the malignant hematologist to consider when designing or evaluating a study with patient?reported outcome measures (PROMs)

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Recurrence after stopping anticoagulants in women with combined oral contraceptive?associated venous thromboembolism: A systematic review and meta?analysis

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Intensity-modulated radiotherapy versus stereotactic body radiotherapy for prostate cancer (PACE-B): 2-year toxicity results from an open-label, randomised, phase 3, non-inferiority trial

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Patient and Healthcare Provider Perspectives on the Implementation of a Web-Based Clinical Communication System for Cancer: A Qualitative Study

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BMS-986012, an Anti–Fucosyl-GM1 Monoclonal Antibody as Monotherapy or in Combination With Nivolumab in Relapsed/Refractory SCLC: Results From a First-in-Human Phase 1/2 Study

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Role of pemetrexed in advanced non-small-cell lung cancer: meta-analysis of randomized controlled trials, with histology subgroup analysis

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Multisystem Immune-Related Adverse Events from Dual-Agent Immunotherapy Use

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Evaluating equity of access and predictors of minimally invasive hysterectomy for endometrial and cervical cancer from 2000 to 2017 in Ontario, Canada: A population‐based cohort study

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Great Debate: Systematic Re-Resection After Macroscopic Complete Unplanned Excision of Soft Tissue Sarcoma

Miura, J., Sabharwal, S., Ghert, M., Karakousis, G., & Roland, C. L. (2024). Great Debate: Systematic Re-Resection After Macroscopic Complete Unplanned Excision of Soft Tissue Sarcoma. Annals of surgical oncology, 31(3), 2047–2050. https://doi.org/10.1245/s10434-023-14780-x

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Gender and Racial Diversity Among Obstetrics and Gynecology Departments and Gynecologic Oncology Divisions in Canada: Are We There Yet?

Mah, S. J., Bellini, J., Pond, G., Reade, C. J., & Nguyen, J. M. V. (2024). Gender and Racial Diversity Among Obstetrics and Gynecology Departments and Gynecologic Oncology Divisions in Canada: Are We There Yet?. Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC, 46(4), 102350. https://doi.org/10.1016/j.jogc.2024.102350

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Impact of smoking status on clinical outcomes in patients with metastatic renal cell carcinoma treated with first-line immune checkpoint inhibitor-based regimens

Saad, E., Gebrael, G., Semaan, K., Eid, M., Saliby, R. M., Labaki, C., Sayegh, N., Wells, J. C., Takemura, K., Ernst, M. S., Lemelin, A., Basappa, N. S., Wood, L. A., Powles, T., Ernst, D. S., Lalani, A. A., et al. (2024). Impact of smoking status on clinical outcomes in patients with metastatic renal cell carcinoma treated with first-line immune checkpoint inhibitor-based regimens. The oncologist, oyae072. Advance online publication. https://doi.org/10.1093/oncolo/oyae072

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Effectiveness of Training Programs About a Palliative Care Approach: A Systematic Review of Intervention Trials for Health Care Professionals

Bainbridge D, Bishop V, Myers J, Marshall D, Stajduhar K, Seow H. Bainbridge D, Bishop V, Myers J, Marshall D, Stajduhar K, Seow H. Journal of Palliative Medicine. 2023 April; 26(4) 564-581.

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Neighborhood Deprivation and Rurality Associated With Patient-Reported Outcomes and Survival in Men With Prostate Cancer in NRG Oncology RTOG 0415

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Frailty and survival among veterans treated with abiraterone or enzalutamide for metastatic castration-resistant prostate cancer

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Pan-Canadian consensus recommendations for proton beam therapy access in Canada

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Hippo pathway dysregulation in gastric cancer: from Helicobacter pylori infection to tumor promotion and progression

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Feasibility and Effectiveness of Self-Management Education and Coaching on Patient Activation for Managing Cancer Treatment Toxicities.

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First look at the baseline characteristics of participants in IRONMAN, the international registry for men with advanced prostate cancer.

Mucci LA, Vinson J, Gerke TA, Hyslop T, Howard L, Dreicer R, Rathkopf DE, Chi KN, Esteban E, Enting D, Bjartell A, Tagawa ST, Nanus DM, Ong M, Barata PC, Hotte SJ, Grant M, Villanti P, Kantoff PW, George DJ. First look at the baseline characteristics of participants in IRONMAN, the international registry for men with advanced prostate cancer. Journal of Clinical Oncology. 2023 Feb: 41(6) :85

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The impact of routine Edmonton symptom assessment system use on receiving palliative care services: results of a population-based retrospective-matched cohort analysis

Barbera L, Sutradhar R, Earle CC, Howell D, Mittman N, Li Q, Thiruchelvam D, Seow H. The impact of routine Edmonton symptom assessment system use on receiving palliative care services: results of a population-based retrospective-matched cohort analysis. BMJ Support Palliat Care. 2023 Oct;13(e1):e144-e149.

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Circulating Growth Differentiation Factor 15 as a Biomarker in Patients with Unresected Locally Advanced Non-Small Cell Lung Cancer Treated with Chemo-Radiotherapy with or without Metformin

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Update on the Management of Stage III NSCLC: Navigating a Complex and Heterogeneous Stage of Disease

Sathiyapalan A, Baloush Z, Ellis PM. Update on the Management of Stage III NSCLC: Navigating a Complex and Heterogeneous Stage of Disease. Curr Oncol. 2023 Oct 29;30(11):9514-9529. doi: 10.3390/curroncol30110689. PMID: 37999109; PMCID: PMC10670056.

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The Effectiveness and Safety of Stereotactic Body Radiation Therapy (SBRT) in the Treatment of Oligoprogressive Breast Cancer: A Systematic Review

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Diagnostic management of acute pulmonary embolism: a prediction model based on a patient data meta-analysis

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Genetic testing practices among specialist physicians who treat prostate cancer: A Canadian cross-sectional survey

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Risk of cancer-specific death among octogenarians with multiple myeloma: A population-based analysis

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Cancer-specific mortality in multiple myeloma: a population-based retrospective cohort study

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Effect of Metformin Versus Placebo on New Primary Cancers in Canadian Cancer Trials Group MA.32: A Secondary Analysis of a Phase III Randomized Double-Blind Trial in Early Breast Cancer

Goodwin PJ, Chen BE, Gelmon KA, Whelan TJ, Ennis M, Lemieux J, Ligibel JA, Hershman DL, Mayer IA, Hobday TJ, Bliss JM, Rastogi P, Rabaglio-Poretti M, Thompson AM, Rea DW, Stos PM, Shepherd LE, Stambolic V, Parulekar WR. Effect of Metformin Versus Placebo on New Primary Cancers in Canadian Cancer Trials Group MA.32: A Secondary Analysis of a Phase III Randomized Double-Blind Trial in Early Breast Cancer. J Clin Oncol. 2023 Dec 10;41(35):5356-5362. doi: 10.1200/JCO.23.00296. Epub 2023 Sep 11. PMID: 37695982; PMCID: PMC10713140.

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von Willebrand factor propeptide variants lead to impaired storage and ER retention in patient?derived endothelial colony?forming cells

Bowman M, Casey L, Selvam SN, Lima PDA, Rawley O, Hinds M, Tuttle A, Grabell J, Iorio A, Walker I, Lillicrap D, James P. von Willebrand factor propeptide variants lead to impaired storage and ER retention in patient?derived endothelial colony?forming cells. 2022 July. 20(7) 1599-1609

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Toxicity Profiles of Systemic Therapies for Advanced Hepatocellular Carcinoma

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The proteomic landscape of glioblastoma recurrence reveals novel and targetable immunoregulatory drivers

Tatari N, Khan S, Livingstone J, Zhai K, Mckenna D, Ignatchenko V, Chokshi C, Gwynne WD, Singh M, Revill S, Mikolajewicz N, Zhu C, Chan J, Hawkins C, Lu J-Q, Provias JP, Ask K, Morrissy S, Brown S, Weiss T, Weller M, Han H, Greenspoon JN, Moffat J, Venugopal C, Boutros PC, Singh SK, Kislinger T. The proteomic landscape of glioblastoma recurrence reveals novel and targetable immunoregulatory drivers. Acta Neuropathologica. 2022 Dec;144(6):1127-1142.

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Carfilzomib usage patterns and outcomes in patients with relapsed multiple myeloma: A multi?institutional report from the Canadian Myeloma Research Group (CMRG) Database

McCurdy A, Louzada M, Venner CP, Visram A, Masih-Khan E, Kardjadj M, Jimenez-Zepeda VH, LeBlanc R, Sebag M, Song K, White D, Mian H, Stakiw J, Reiman A, Aslam M, Kotb R, Gul E, Reece D. Carfilzomib usage patterns and outcomes in patients with relapsed multiple myeloma: A multi-institutional report from the Canadian Myeloma Research Group (CMRG) Database. EJHaem. 2022 Aug 31;3(4):1252-1261.

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Physician and Surgeon Communication Assessed via the Pathology Requisition in a Regional Laboratory Over Ten Years

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Response and innovations of advanced practice nurses during the COVID-19 pandemic: A scoping review

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Recombinant Newcastle disease viruses expressing immunological checkpoint inhibitors induce a pro-inflammatory state and enhance tumor-specific immune responses in two murine models of cancer

Santry LA, van Vloten JP, AuYeung AWK, Mould RC, Yates JGE, McAusland TM, Petrik JJ, Major PP, et al. Recombinant Newcastle disease viruses expressing immunological checkpoint inhibitors induce a pro-inflammatory state and enhance tumor-specific immune responses in two murine models of cancer. Front Microbiol. 2024 Jan 24;15:1325558. doi: 10.3389/fmicb.2024.1325558. PMID: 38328418; PMCID: PMC10847535.

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Disease control outcomes of stereotactic body radiation therapy or moderate hypo‐fractionation for prostate cancer: Real‐world experience at two Canadian centers

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Sex-Based Analysis of Quality Indicators of End-of-Life Care in Gastrointestinal Malignancies

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An Ontario Health (Cancer Care Ontario) Clinical Practice Guideline: Surveillance Strategies in Patients with Stage I, II, III or Resectable IV Melanoma Who Were Treated with Curative Intent

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Concurrent BCR‐ABL1 and core binding factor beta rearrangement in de novo acute myeloid leukemia: A case report and review of literature

Salter, B., Ge, S., Tam, A., Demczuk, S., Butcher, D., McCready, E., & Khalaf, D. (2024). Concurrent BCR-ABL1 and core binding factor beta rearrangement in de novo acute myeloid leukemia: A case report and review of literature. eJHaem, 5(3), 607–615. https://doi.org/10.1002/jha2.895

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Cardiovascular outcomes in children with Kawasaki disease: a population-based cohort study

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Use of Systemic Therapies for Treatment of Psoriasis in Patients with a History of Treated Solid Tumours: Inference-Based Guidance from a Multidisciplinary Expert Panel

Papp KA, Melosky B, Sehdev S, Hotte SJ, Beecker JR, Kirchhof MG, Turchin I, Dutz JP, Gooderham MJ, Gniadecki R, Hong C-H, Lambert J, Lynde CW, Prajapati VH, Vender RB.Use of Systemic Therapies for Treatment of Psoriasis in Patients with a History of Treated Solid Tumours: Inference-Based Guidance from a Multidisciplinary Expert Panel. Dermatology and Therapy. 2023 April; 13(4) 867-889.

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Indolent lymphoma: Bendamustine, rituximab and acalabrutinib in Waldenstroms Macroglobulinemia (BRAWM)

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AGREE-S: AGREE II extension for surgical interventions: appraisal instrument

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Targeting tumor-stroma communication by blocking endothelin-1 receptors sensitizes high-grade serous ovarian cancer to PARP inhibition

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LSD1 inhibition modulates transcription factor networks in myeloid malignancies

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Practice patterns and predictors of treatment intensification in patients with metastatic castration-sensitive prostate cancer.

Gotto GT, Yip SM, Shayegan B, O'Sullivan DE, Wallis CJD, Basappa NS, Cagiannos I, Hamilton RJ, Ferrario C, Fernandes R, Danielson B, Saad F, Hotte SJ, Brenner DR, Cheung WY, Boyne DJ, Chan K, Osborne B, Zardan A, Malone S. Practice patterns and predictors of treatment intensification in patients with metastatic castration-sensitive prostate cancer. Journal of Clinical Oncology. 2023 Feb: 41(6):76

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Quality of life assessment in older patients with Newly Diagnosed Multiple Myeloma.

Mian H, Fiala M, Pond G, Wildes T. Quality of life assessment in older patients with newly-diagnosed multiple myeloma. Clinical Lymphoma Myeloma and Leukemia . 2019 Oct ;19(10):e232–3.

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Final Results from a Prospective Randomized Pilot Trial of Stereotactic Body Radiation Therapy vs. Radiofrequency Ablation for the Management of Small Renal Masses (RADSTER)

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A qualitative study on healthcare professional and patient perspectives on nurse-led virtual prostate cancer survivorship care

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Surgical Management of Meningiomas Involving the Torcula, Transverse Sinus, and Jugular Bulb: A Technical Note and Review of the Literature

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Survival in Metastatic Renal Cell Carcinoma Treated With Immunotherapy and Stereotactic Radiation Therapy or Immunotherapy Alone: A National Cancer Database Analysis

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Breast tissue analysis using a clinically compatible combined time-resolved fluorescence and diffuse reflectance (TRF-DR) system

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CORR Insights®: What Factors Are Associated With Stem Breakage in Distal Femoral Endoprosthetic Replacements Undertaken for Primary Bone Tumors?

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Intensity of end-of-life care among children with life-threatening conditions: a national population-based observational study

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Shorter Durations of Anti-HER2 Therapy for Patients with Early-Stage, HER2-Positive Breast Cancer: The Physician Perspective

Bradbury M, Savard MF, Vandermeer L, Clemons L, Pond G, Hilton J, Clemons M, McGee S. Shorter Durations of Anti-HER2 Therapy for Patients with Early-Stage, HER2-Positive Breast Cancer: The Physician Perspective. Curr Oncol. 2023 Dec 14;30(12):10477-10487. doi: 10.3390/curroncol30120763. PMID: 38132397; PMCID: PMC10742686.

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Metformin-induced reductions in tumor growth involves modulation of the gut microbiome

Broadfield LA, Saigal A, Szamosi JC, Hammill JA, Bezverbnaya K, Wang D, Gautam J, Tsakiridis EE, Di Pastena F, McNicol J, Wu J, Syed S, Lally JSV, Raphenya AR, Blouin M-J, Pollak M, Sacconi A, Blandino G, McArthur AG, Schertzer JD, Surette MG, Collins SM, Bramson JL, Muti P, Tsakiridis T, Steinberg GR. Metformin-induced reductions in tumor growth involves modulation of the gut microbiome. Molecular Metabolism. 2022 July; 61

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Outcomes after autologous hematopoietic cell transplantation in POEMS syndrome and comparison with multiple myeloma

D'Souza A, Kansagra A, Dispenzieri A, Fraser R, Estrada-Merly N, Sidana S, Nishihori T, Hansen DK, Anderson LD, Banerjee R, Bumma N, Dhakal B, Khouri J, Landau H, Lee CH, Mian H, Nathan S, Savani BN, Kumar SK, Qazilbash MH, Shah N. Outcomes after autologous hematopoietic cell transplantation in POEMS syndrome and comparison with multiple myeloma. Blood Advances. 2022 Jul 12;6(13):3991-3995

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Perioperative management of myeloproliferative neoplasms: A pan?Canadian physician survey and international expert opinion

Szuber N, Toliopoulos P, Busque L, Cerquozzi S, Foltz L, Gupta V, Tefferi A, Vannucchi AM, Hillis C, Leber B, Maze D, Prchal J, Olney HJ, Sirhan S. Perioperative management of myeloproliferative neoplasms: A pan?Canadian physician survey and international expert opinion. American Journal of Hematology. 2022 Dec;97(12):E466-E469.

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Low-grade serous carcinoma (LGSC): A Canadian multicenter review of practice patterns and patient outcomes

Scott SA, Llaurado Fernandez M, Kim H, Elit L, Nourmoussavi M, Glaze S, Roberts L, Offman SL, Rahimi K, Lytwyn A, Sur M, Gilks CB, Matheson K, Köbel M, Dawson A, Tinker AV, Kwon JS, Hoskins P, Santos JL, Cheung A, Provencher D, Carey MS; Canadian LGSC Community of Practice (GOC-CoP). Low-grade serous carcinoma (LGSC): A Canadian multicenter review of practice patterns and patient outcomes. Gynecol Oncol. 2020 Apr;157(1):36-45.

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Barriers to Access: Global Variability in Implementing Treatment Advances in Lung Cancer.

Febbraro M, Gheware A, Kennedy T, Jain D, de Moraes FY, Juergens R. Barriers to Access: Global Variability in Implementing Treatment Advances in Lung Cancer. Am Soc Clin Oncol Educ Book. 2022 Apr;42:1-7. doi: 10.1200/EDBK_351021. PMID: 35427189.

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Surveillance evaluations in patients with stage I, II, III, or resectable IV melanoma who were treated with curative intent: A systematic review

Rajagopal S, Yao X, Abadir W, Baetz TD, Easson A, Knight G, McWhirter E, Nessim C, Rosen CF, Sun A, Wright FC, Petrella TM. Surveillance evaluations in patients with stage I, II, III, or resectable IV melanoma who were treated with curative intent: A systematic review. Surg Oncol. 2024 Jun;54:102077. doi: 10.1016/j.suronc.2024.102077. Epub 2024 Apr 10. PMID: 38657486.

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Breast cancer learning health system: Patient information from a data and analytics platform characterizes care provided

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Evaluating the efficacy of artificial intelligence tools for the automation of systematic reviews in cancer research: A systematic review

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177Lu-PSMA-617 in Metastatic Castration-Resistant Prostate Cancer: A Review of the Evidence and Implications for Canadian Clinical Practice

Chi, K. N., Yip, S. M., Bauman, G., Probst, S., Emmenegger, U., Kollmannsberger, C. K., Martineau, P., Niazi, T., Pouliot, F., Rendon, R., Hotte, S. J., Laidley, D. T., & Saad, F. (2024). 177Lu-PSMA-617 in Metastatic Castration-Resistant Prostate Cancer: A Review of the Evidence and Implications for Canadian Clinical Practice. Current oncology (Toronto, Ont.), 31(3), 1400–1415. https://doi.org/10.3390/curroncol31030106

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Bilateral Oophorectomy and All-Cause Mortality in Women With BRCA1 and BRCA2 Sequence Variations

Kotsopoulos, J., Gronwald, J., Huzarski, T., Møller, P., Pal, T., McCuaig, J. M., Singer, C. F., Karlan, B. Y., Aeilts, A., Eng, C., Eisen, A., Bordeleau, L., et al. (2024). Bilateral Oophorectomy and All-Cause Mortality in Women With BRCA1 and BRCA2 Sequence Variations. JAMA oncology, 10(4), 484–492. https://doi.org/10.1001/jamaoncol.2023.6937

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Immigration Status and Breast Cancer Surgery Quality of Care Metrics: A Population-Level Analysis

Parvez, E., Bogach, J., Kirkwood, D., Pond, G., Doumouras, A., Hodgson, N., & Levine, M. (2024). Immigration Status and Breast Cancer Surgery Quality of Care Metrics: A Population-Level Analysis. Annals of surgical oncology, 31(7), 4518–4526. https://doi.org/10.1245/s10434-024-15250-8

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Evaluation of Trends in Treatment of Metastatic Hormone Sensitive Prostate Cancer (mHSPC) Across Canada During the COVID-19 Pandemic

Stecca CE, Jiang DM, Veitch Z, Hotte SJ, Alimohamed N, Wood L, Sridhar SS. Evaluation of Trends in Treatment of Metastatic Hormone Sensitive Prostate Cancer (mHSPC) Across Canada During the COVID-19 Pandemic. Clinical Genitourinary Cacner. 2023 April; 21(2) 273-277.

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Prevalence of Thyroid Transcription Factor-1 (TTF-1)-Negative Small Cell Carcinoma and Napsin A Positivity in Small Cell Carcinoma in a Cross-Sectional Study of Lung Core Biopsies

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Breast cancer mortality in 500 000 women with early invasive breast cancer in England, 1993-2015: population based observational cohort study

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Oncosuppressive miRNAs loaded in lipid nanoparticles potentiate targeted therapies in BRAF-mutant melanoma by inhibiting core escape pathways of resistance

Fattore L, Cafaro G, Di Martile M, Campani V, Sacconi A, Liguoro D, Marra E, Bruschini S, Stoppoloni D, Cirombella R, De Nicola F, Pallocca M, Ruggiero CF, Castaldo V, Catizone A, Del Bufalo D, Viglietto G, Vecchione A, Blandino G, Aurisicchio L, Fanciulli M, Ascierto PA, De Rosa G, Mancini R, Ciliberto G. Oncosuppressive miRNAs loaded in lipid nanoparticles potentiate targeted therapies in BRAF-mutant melanoma by inhibiting core escape pathways of resistance. Oncogene. 2023 Jan; 42(4); 293-307.

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18F-DCFPyL (PSMA) PET as a radiotherapy response assessment tool in metastatic prostate cancer

Mesci A, Ahmadi E, Ali A, Gouran-Savadkoohi M, Evelyn Tsakiridis E, Biziotis OD, Chow T, Kapoor A, Sur M, Steinberg GR, Liu S, Zukotynski K, Tsakiridis T. 18F-DCFPyL (PSMA) PET as a radiotherapy response assessment tool in metastatic prostate cancer. Clin Transl Radiat Oncol. 2023 Jan 18;39:100583

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Antiviral therapy defiant mixed viral retinitis post hematopoietic allogeneic stem cell transplant

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Plasma phosphocreatine (PC) as a predictive biomarker for immune checkpoint inhibition in patients with refractory metastatic colorectal cancer (mCRC): Analysis of the CCTG CO.26 trial.

Ma LX, Loree JM, Jonker DJ, Kennecke HF, Berry SR, Couture F, Ahmad CE, Goffin JR, Kavan P, Harb M, Colwell B, Samimi S, Samson B, Abbas T, Aucoin N, Aubin F, Koski SL, Tu D, O'Callaghan CJ, Chen EX. Plasma phosphocreatine (PC) as a predictive biomarker for immune checkpoint inhibition in patients with refractory metastatic colorectal cancer (mCRC): Analysis of the CCTG CO.26 trial. Journal of Clinical Oncology. 2023 Feb:41(6):183

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Performance of externally validated machine learning models based on histopathology images for the diagnosis, classification, prognosis, or treatment outcome prediction in female breast cancer: A systematic review

Gonzalez R, Nejat P, Saha A, Campbell CJV, Norgan AP, Lokker C. Performance of externally validated machine learning models based on histopathology images for the diagnosis, classification, prognosis, or treatment outcome prediction in female breast cancer: A systematic review. Journal of Pathology Informatics . 2024 Dec 1 ;15:100348

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Evaluation of Volumetric Response Assessment from Stereotactic Ablative Radiotherapy (SABR) for Renal Cell Carcinoma (RCC)

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Presentation and outcomes of KRAS G12C mutant non-small cell lung cancer patients with stage IV disease at diagnosis (de novo) versus at recurrence

Esfahanian N, Chan SWS, Zhan LJ, Brown MC, Khan K, Lee J, et al. Presentation and outcomes of KRASG12C mutant non-small cell lung cancer patients with stage IV disease at diagnosis (De novo) versus at recurrence. Cancer Treatment and Research Communications 2023 Jan ;37:100774.

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Can routinely collected administrative data effectively be used to evaluate and validate endpoints used in breast cancer clinical trials? Protocol for a scoping review of the literature

Shah H, Wolfe D, Clemons M, Liu M, Thavorn K, Veroniki AA, Lunny C, Pond G, McGee S, Skidmore B, Arnaout A, Hutton B. Can routinely collected administrative data effectively be used to evaluate and validate endpoints used in breast cancer clinical trials? Protocol for a scoping review of the literature. Syst Rev. 2023 Jul 8;12(1):117. doi: 10.1186/s13643-023-02283-5. PMID: 37422656; PMCID: PMC10329388.

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Constitutive expression of interleukin-27 diminishes proinflammatory cytokine production without impairing effector function of engineered T cells

Afsahi A, Burchett R, Baker CL, Moore AE, Bramson JL. Constitutive expression of interleukin-27 diminishes proinflammatory cytokine production without impairing effector function of engineered T cells. Cytotherapy. 2023 Sep;25(9):913-919. doi: 10.1016/j.jcyt.2023.05.004. Epub 2023 Jun 10. PMID: 37306644.

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Long-Term Toxicity in Patients Receiving Radiotherapy for Ultracentral Stage I Non-Small Cell Lung Cancer – A Secondary Analysis of the LUSTRE Randomized Trial

Wu, C. H. D., Wierzbicki, M., Parpia, S., Kundapur, V., Bujold, A., Filion, E. J., Lau, H., Faria, S., Ahmed, N., Leong, N., Okawara, G., Hirmiz, K. J., Owen, T. E., Louie, A. V., Wright, J., Whelan, T. J., & Swaminath, A. (2023). Long-term toxicity in patients receiving radiotherapy for ultracentral stage I non-small cell lung cancer – a secondary analysis of the Lustre Randomized Trial. International Journal of Radiation Oncology*Biology*Physics, 117(2). https://doi.org/10.1016/j.ijrobp.2023.06.636

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Canagliflozin mediates tumor suppression alone and in combination with radiotherapy in non‐small cell lung cancer (NSCLC) through inhibition of HIF‐1α

Biziotis OD, Tsakiridis EE, Ali A, Ahmadi E, Wu J, Wang S, Mekhaeil B, Singh K, Menjolian G, Farrell T, Abdulkarim B, Sur RK, Mesci A, Ellis P, Berg T, Bramson JL, Muti P, Steinberg GR, Tsakiridis T. Canagliflozin mediates tumor suppression alone and in combination with radiotherapy in non-small cell lung cancer (NSCLC) through inhibition of HIF-1α. Mol Oncol. 2023 Nov;17(11):2235-2256. doi: 10.1002/1878-0261.13508. Epub 2023 Aug 27. PMID: 37584455; PMCID: PMC10620129.

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Redefining attrition in multiple myeloma (MM): a Canadian Myeloma Research Group (CMRG) analysis

McCurdy A, Mian H, LeBlanc R, Jimenez-Zepeda VH, Su J, Masih-Khan E, Visram A, Louzada M, Song K, White D, Sebag M, Stakiw J, Reiman A, Aslam M, Bergstrom D, Kotb R, Kaedbey R, Gul E, Reece D, Venner CP. Redefining attrition in multiple myeloma (MM): a Canadian Myeloma Research Group (CMRG) analysis. Blood Cancer J. 2023 Jul 20;13(1):111. doi: 10.1038/s41408-023-00883-x. Erratum in: Blood Cancer J. 2023 Aug 28;13(1):129. doi: 10.1038/s41408-023-00888-6. PMID: 37474492; PMCID: PMC10359388.

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Pembrolizumab plus chemotherapy versus chemotherapy in untreated advanced pleural mesothelioma in Canada, Italy, and France: a phase 3, open-label, randomised controlled trial

Chu Q, Perrone F, Greillier L, Tu W, Piccirillo MC, Grosso F, Lo Russo G, Florescu M, Mencoboni M, Morabito A, Cecere FL, Ceresoli GL, Dawe DE, Zucali PA, Pagano M, Goffin JR, et al. Pembrolizumab plus chemotherapy versus chemotherapy in untreated advanced pleural mesothelioma in Canada, Italy, and France: a phase 3, open-label, randomised controlled trial. Lancet. 2023 Dec 16;402(10419):2295-2306. doi: 10.1016/S0140-6736(23)01613-6. Epub 2023 Nov 3. PMID: 37931632.

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Sensitivity analysis in clinical trials: three criteria for a valid sensitivity analysis

Parpia S, Morris TP, Phillips MR, Wykoff CC, Steel DH, Thabane L, Bhandari M, Chaudhary V. Sensitivity analysis in clinical trials: three criteria for a valid sensitivity analysis. Eye. 2-22 Nov; 36(11) 2073-2074

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Comparison of outcomes between abdominal, minimally invasive and combined vaginal-laparoscopic hysterectomy in patients with stage IAI/IA2 cervical cancer: 4C (Canadian Cervical Cancer Collaborative) study

Piedimonte S, Pond GR, Plante M, Nelson G, Kwon J, Altman A, Feigenberg T, Elit L, Lau S, Sabourin J, Willows K, Aubrey C, Jang J-H, Teo-Fortin L-A, Cockburn N, Saunders N-B, Shamiya S, Helpman L, Vicus D, Collaborative OBOTCCCC. Comparison of outcomes between abdominal, minimally invasive and combined vaginal-laparoscopic hysterectomy in patients with stage IAI/IA2 cervical cancer: 4C (Canadian Cervical Cancer Collaborative) study. Gynecologic Oncology. 2022 Aug;166(2):230-235.

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Why do we not reverse the path? Stress can cause depression, reduction of brain-derived neurotrophic factor and increased inflammation

Claro AE, Palanza C, Mazza M, Rizzi A, Tartaglione L, Marano G, Muti-Schuenemann G, Rigoni M, Muti P, Pontecorvi A, Janiri L, Sani G, Pitocco D. Why do we not reverse the path? Stress can cause depression, reduction of brain-derived neurotrophic factor and increased inflammation. World Journal of Psychiatry. 2022 Sep 19; 12(9): 1264–1267.

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Quality of End-of-Life Care in Gastrointestinal Cancers: A 13-Year Population-Based Retrospective Analysis in Ontario, Canada

Lees CS, Seow H, Chan KK, Gayowsky A, Sinnarajah A. Quality of End-of-Life Care in Gastrointestinal Cancers: A 13-Year Population-Based Retrospective Analysis in Ontario, Canada. Curr Oncol. 2022 Nov 24;29(12):9163-9171.

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5-year outcomes after stereotactic ablative body radiotherapy for primary renal cell carcinoma: an individual patient data meta-analysis from IROCK (the International Radiosurgery Consortium of the Kidney)

Siva S, Ali M, Correa RJM, Muacevic A, Ponsky L, Ellis RJ, Lo SS, Onishi H, Swaminath A, McLaughlin M, Morgan SC, Cury FL, Teh BS, Mahadevan A, Kaplan ID, Chu W, Grubb W, Hannan R, Staehler M, Warner A, Louie AV. 5-year outcomes after stereotactic ablative body radiotherapy for primary renal cell carcinoma: an individual patient data meta-analysis from IROCK (the International Radiosurgery Consortium of the Kidney). Lancet Oncol. 2022 Dec;23(12):1508-1516. doi: 10.1016/S1470-2045(22)00656-8. Epub 2022 Nov 16. PMID: 36400098.

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Pilot and feasibility trials in surgery are incompletely reported according to the CONSORT checklist: a meta-research study

McKechnie T, Kazi T, Wang A, Zhang S, Thabane A, Nanji K, Staibano P, Park LJ, Doumouras A, Eskicioglu C, Thabane L, Parpia S, Bhandari M. Pilot and feasibility trials in surgery are incompletely reported according to the CONSORT checklist: a meta-research study. J Clin Epidemiol. 2024 Mar 27;170:111335. doi: 10.1016/j.jclinepi.2024.111335. Epub ahead of print. PMID: 38548230.

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Treatment Pattern, Healthcare Resource Utilization and Symptom Burden Among Patients with Triple Class Exposed Multiple Myeloma: A Population-Based Cohort Study

Mian H, Seow H, Pond GR, Gayowsky A, Foley R, Balistky A, Ebraheem M, Cipkar C, Sapru H, Mohyuddin GR, Hadidi SA, Visram A. Treatment Pattern, Healthcare Resource Utilization and Symptom Burden Among Patients with Triple Class Exposed Multiple Myeloma: A Population-Based Cohort Study. Clin Lymphoma Myeloma Leuk. 2024 Jun;24(6):e227-e234. doi: 10.1016/j.clml.2024.02.006. Epub 2024 Feb 14. PMID: 38431522.

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Belantamab mafodotin, pomalidomide and dexamethasone in refractory multiple myeloma: a phase 1/2 trial

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MRI Surveillance and Breast Cancer Mortality in Women With BRCA1 and BRCA2 Sequence Variations

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Corrigendum to “Outcomes for International Metastatic Renal Cell Carcinoma Database Consortium Prognostic Groups in Contemporary First-line Combination Therapies for Metastatic Renal Cell Carcinoma” [Eur Urol 2023]

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Neurocognitive impairment, neurobehavioral symptoms, fatigue, sleep disturbance, and depressive symptoms in patients with newly diagnosed glioblastoma.

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Definitive High-Dose Radiotherapy for Primary Vulvar Cancer: The DRIVE Multicenter Cohort Study

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Development and Validation of an Indicator for Oncofertility Care in Ontario, Canada, for Adolescents and Young Adults with Cancer

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Treatment Modalities to Manage Hepatocellular Carcinoma Patients with Portal Vein Thrombus: A Systematic Review and Meta-Analysis

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Ki67 assessment protocol as an integral biomarker for avoiding radiotherapy in the LUMINA breast cancer trial

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What’s New in Musculoskeletal Tumor Surgery

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Transfusion thresholds in myelodysplastic syndrome—Helping patients live better

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The impact of the Caremongering social media movement: A convergent parallel mixed?methods study

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Therapy for Stage IV Non–Small-Cell Lung Cancer With Driver Alterations: ASCO Living Guideline

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Use of the Toxicity Index in Evaluating Adverse Events in Anal Cancer Trials

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Chemo-Immunotherapy in First Line Extensive Stage Small Cell Lung Cancer (ES-SCLC): A Systematic Review and Meta-Analysis

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Factors Influencing the Decision of Individuals with Breast Cancer to Join an Exercise Oncology Trial

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The Nurse Practitioner Role in Complex Malignant Hematology: A Qualitative Descriptive Study

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High-Sensitivity Cardiac Troponin I for Long-Term Cardiovascular Risk Stratification in a Cancer Clinic Population

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Cell Therapy Transplant Canada (CTTC) Consensus-Based Guideline 2024 for Management and Treatment of Chronic Graft-Versus-Host Disease and Future Directions for Development

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A structured oral chemotherapy teaching tool to improve adherence in adults with multiple myeloma: A pilot randomized controlled trial

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Emergency physician gender and head computed tomography orders for older adults who have fallen

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Rurality index score and pediatric neuro-oncological outcome in Ontario.

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Impact of bortezomib based versus lenalidomide maintenance therapy on outcomes of patients with high risk multiple myeloma

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Canadian Consensus Recommendations on the Management of Extensive-Stage Small-Cell Lung Cancer

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Olaparib Efficacy in Patients with Metastatic Castration-resistant Prostate Cancer and BRCA1, BRCA2 or ATM Alterations Identified by Testing Circulating Tumor DNA

Matsubara N, de Bono J, Olmos D, Procopio G, Kawakami S, Ürün Y, van Alphen R, Flechon A, Carducci MA, Choi YD, Hotte SJ, Korbenfeld E, Kramer G, Agarwal N, Chi KN, Dearden S, Gresty C, Kang J, Poehlein C, Harrington EA, Hussain M. Olaparib Efficacy in Patients with Metastatic Castration-resistant Prostate Cancer and BRCA1, BRCA2, or ATM Alterations Identified by Testing Circulating Tumor DNA. Clin Cancer Res. 2023 Jan 4;29(1):92-99.

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Decision-making factors for an autologous stem cell transplant for older adults with newly diagnosed multiple myeloma: A qualitative analysis

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Momelotinib versus danazol in symptomatic patients with anaemia and myelofibrosis (MOMENTUM): results from an international, double-blind, randomised, controlled, phase 3 study

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Pembrolizumab in combination with gemcitabine and cisplatin compared with gemcitabine and cisplatin alone for patients with advanced biliary tract cancer (KEYNOTE-966): a randomised, double-blind, placebo-controlled, phase 3 trial

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Accuracy of physicians’ intuitive risk estimation in the diagnostic management of pulmonary embolism: an individual patient data meta-analysis

van Maanen R, Martens ESL, Takada T, Roy PM, de Wit K, Parpia S, Kraaijpoel N, Huisman MV, Wells PS, Le Gal G, Righini M, Freund Y, Galipienzo J, van Es N, Blom JW, Moons KGM, Rutten FH, van Smeden M, Klok FA, Geersing GJ, Luijken K. Accuracy of physicians' intuitive risk estimation in the diagnostic management of pulmonary embolism: an individual patient data meta-analysis. J Thromb Haemost. 2023 Oct;21(10):2873-2883.

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Systemic Therapy for Small-Cell Lung Cancer: ASCO-Ontario Health (Cancer Care Ontario) Guideline.

Khurshid H, Ismaila N, Bian J, Dabney R, Das M, Ellis P, Feldman J, Hann C, Kulkarni S, Laskin J, Manochakian R, Mishra DR, Preeshagul I, Reddy P, Saxena A, Weinberg F, Kalemkerian GP. Systemic Therapy for Small-Cell Lung Cancer: ASCO-Ontario Health (Cancer Care Ontario) Guideline. J Clin Oncol. 2023 Dec 10;41(35):5448-5472.

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Seeing the random forest through the decision trees. Supporting learning health systems from histopathology with machine learning models: Challenges and opportunities

Gonzalez R, Saha A, Campbell CJV, Nejat P, Lokker C, Norgan AP. Seeing the random forest through the decision trees. Supporting learning health systems from histopathology with machine learning models: Challenges and opportunities. Journal of Pathology Informatics. 2024 Dec ];15:100347

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Leukemic progenitor compartment serves as a prognostic measure of cancer stemness in patients with acute myeloid leukemia

Boyd AL, Lu J, Hollands CG, Alsostovar L, Murali S, Reid JC, Ye W, Vandersluis S, Johnson P, ElRafie A, Porras DP, Xenocostas D, Leber A, Leber B, Foley R, Trus M, Berg T, Kawata E, Xenocostas A, Bhatia M. Leukemic progenitor compartment serves as a prognostic measure of cancer stemness in patients with acute myeloid leukemia. Cell Rep Med. 2023 Jul 18;4(7):101108. doi: 10.1016/j.xcrm.2023.101108. Epub 2023 Jul 10. PMID: 37433297; PMCID: PMC10394166.

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Diagnosis and Management of Cardiovascular Effects of Bruton’s Tyrosine Kinase Inhibitors

Aghel N, Baro Vila RC, Lui M, Hillis C, Leong DP. Diagnosis and Management of Cardiovascular Effects of Bruton's Tyrosine Kinase Inhibitors. Curr Cardiol Rep. 2023 Sep;25(9):941-958. doi: 10.1007/s11886-023-01916-4. Epub 2023 Jul 27. PMID: 37498449.

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Circulating Growth Differentiation Factor 15 as a Biomarker in Patients with Unresected Locally Advanced Non-Small Cell Lung Cancer Treated with Chemo-Radiotherapy with or without Metformin

Di Pastena, F., Pond, G., Ahmadi, E., Tsakiridis, E. E., Steinberg, G. R., & Tsakiridis, T. (2023). Circulating growth differentiation factor 15 as a biomarker in patients with unresected locally advanced non-small cell lung cancer treated with chemo-radiotherapy with or without metformin. International Journal of Radiation Oncology*Biology*Physics, 117(2). https://doi.org/10.1016/j.ijrobp.2023.06.678

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Pembrolizumab-induced immune-related sclerosing cholangitis

Li Y, Stewart L, Tang S, McWhirter E. Pembrolizumab-induced immune-related sclerosing cholangitis. BMJ Case Rep. 2023 Nov 1;16(11):e256125. doi: 10.1136/bcr-2023-256125. PMID: 37914171; PMCID: PMC10626897.

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Correction: Redefining attrition in multiple myeloma (MM): a Canadian Myeloma Research Group (CMRG) analysis

McCurdy A, Mian H, LeBlanc R, Jimenez-Zepeda VH, Su J, Masih-Khan E, Visram A, Louzada M, Song K, White D, Sebag M, Stakiw J, Reiman A, Aslam M, Bergstrom D, Kotb R, Kaedbey R, Gul E, Reece D, Venner CP. Correction: Redefining attrition in multiple myeloma (MM): a Canadian Myeloma Research Group (CMRG) analysis. Blood Cancer J. 2023 Aug 28;13(1):129. doi: 10.1038/s41408-023-00888-6. Erratum for: Blood Cancer J. 2023 Jul 20;13(1):111. doi: 10.1038/s41408-023-00883-x. PMID: 37635183; PMCID: PMC10460788.

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Locoregional Ablative Radiotherapy for Breast Cancer Patients Unsuitable for Surgical Resection

Moore-Palhares D, Chen H, Khan BM, McCann C, Bosnic S, Hahn E, Soliman H, Czarnota G, Karam I, Rakovitch E, Lee J, Vesprini D. Locoregional Ablative Radiation Therapy for Patients With Breast Cancer Unsuitable for Surgical Resection. Pract Radiat Oncol. 2023 Dec 26:S1879-8500(23)00346-6. doi: 10.1016/j.prro.2023.12.003. Epub ahead of print. PMID: 38154688.

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Effectiveness of registered nurses on patient outcomes in primary care: a systematic review

Lukewich J, Martin-Misener R, Norful AA, Poitras M-E, Bryant-Lukosius D, Asghari S, Marshall EG, Mathews M, Swab M, Ryan D, Tranmer J. Effectiveness of registered nurses on patient outcomes in primary care: a systematic review. BMC Services Research. 2022 Dec; 22(1) 740

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Discordance between Immunohistochemistry and Erb-B2 Receptor Tyrosine Kinase 2 mRNA to Determine Human Epidermal Growth Factor Receptor 2 Low Status for Breast Cancer

Xu K, Bayani J, Mallon E, Pond GR, Piper T, Hasenburg A, Markopoulos CJ, Dirix L, Seynaeve CM, van de Velde CJH, Rea DW, Bartlett JMS. Discordance between Immunohistochemistry and Erb-B2 Receptor Tyrosine Kinase 2 mRNA to Determine Human Epidermal Growth Factor Receptor 2 Low Status for Breast Cancer. Journal of Molecular Diagnostics. 2022 Jul;24(7):775-783.

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Disparities in the survival of endometrial cancer patients in a public healthcare system: A population-based cohort study

Helpman L, Pond GR, Elit L, Anderson LN, Kong I, Schnarr K, Seow H. Disparities in the survival of endometrial cancer patients in a public healthcare system: A population-based cohort study. Gynecologic Oncology. 2022 Dec;167(3):532-539.

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Assessing knowledge, attitudes and belief toward HPV vaccination of parents with children aged 9–14 years in rural communities of Northwest Cameroon: a qualitative study

Elit L, Ngalla C, Afugchwi GM, Tum E, Domgue JF, Nouvet E. Assessing knowledge, attitudes and belief toward HPV vaccination of parents with children aged 9-14 years in rural communities of Northwest Cameroon: a qualitative study. BMJ Open. 2022 Nov 15;12(11):e068212.

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A Survey-Based Study on Physical Activity Promotion for Individuals with a Current or Past Diagnosis of Cancer in Canada

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Real-world Assessment of Clinical Outcomes in Patients with Metastatic Renal Cell Carcinoma with or Without Sarcomatoid Features Treated with First-line Systemic Therapies

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Advanced Practice Nursing Titles and Roles in Cancer Care: A Scoping Review

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What is your count? An observational study of lymph node counting in 2,028 colorectal cancer resections

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Supporting the Journey Home: The Process of Co-designing an Education Program to Strengthen Palliative Care Capacity in First Nations Communities

Seow, H., Vautour, J., Bishop, V., Antone, C., Belleau, T., Corbiere, B., Fruch, V., McCormick, L., Monture, L., Civak, M., Jyothi Kumar, S., McMillan, K., Bainbridge, D., & Cano, R. (2024). Supporting the journey home: The process of co-designing an education program to strengthen palliative care capacity in First Nations communities. International Journal of Indigenous Health, 19(1). https://doi.org/10.32799/ijih.v19i1.40944

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Acute Toxicity Results from the Randomized Assessment of Cisplatin Dosing Interval for Ototoxicity (RADIO) Trial Comparing Chemoradiation (CRT) with Cisplatin Q3weekly to Weekly for Locally Advanced Squamous Cell Carcinoma of the Head and neck (LASCCHN)

Winquist, E., Meyers, B. M., Smoragiewicz, M., Stewart, P., Ghedira, S., Bordeleau, L., Chan, K., Hotte, S. J., Parker, C., Francis, P., Mortuza, S., Bailey, L., Andrews, J., Black, M., Hickling, C., Palma, D. A., Nichols, A., Kim, R., Pond, G., & Kuruvilla, S. (2024). Acute toxicity results from the randomized assessment of Cisplatin dosing interval for ototoxicity (radio) trial comparing chemoradiation (CRT) with Cisplatin q3weekly to weekly for locally advanced squamous cell carcinoma of the head and neck (LASCCHN). International Journal of Radiation Oncology*Biology*Physics, 118(5). https://doi.org/10.1016/j.ijrobp.2024.01.027

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REporting quality of PilOt randomised controlled trials in surgery (REPORTS): a methodological survey protocol

McKechnie T, Kazi T, Wang A, Zhang S, Thabane A, Nanji K, Doumouras AG, Eskicioglu C, Thabane L, Parpia S, Bhandari M. REporting quality of PilOt randomised controlled trials in surgery (REPORTS): a methodological survey protocol. BMJ Open. 2024 Apr 23;14(4):e085293. doi: 10.1136/bmjopen-2024-085293. PMID: 38658008; PMCID: PMC11043721.

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BRACHY: A Randomized Trial to Evaluate Symptom Improvement in Advanced Non-Small Cell Lung Cancer Treated With External Beam Radiation With or Without High-Dose-Rate Intraluminal Brachytherapy

Sur R, Pond G, Falkson C, Pan M, Wright J, Bezjak A, Dagnault A, Yu E, Almahmudi M, Puksa S, Gopaul D, Tsakiridis T, Swaminath A, Ellis P, Whelan T. BRACHY: A Randomized Trial to Evaluate Symptom Improvement in Advanced Non-Small Cell Lung Cancer Treated With External Beam Radiation With or Without High-Dose-Rate Intraluminal Brachytherapy. International Journey of Radiation Oncology. 2023 July; 116(3) 601-610.

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Health-related quality of life in early-stage Hodgkin lymphoma: a longitudinal analysis of the ABVD arm in the randomized controlled trial HD.6

Mian H, Ringash J, Meyer R, Hay AE, Shepherd L, Djurfeldt M, Winter JN, Sussman J, Pater J, Chen BE, Prica A. Health-related quality of life in early-stage Hodgkin lymphoma: a longitudinal analysis of the ABVD arm in the randomized controlled trial HD.6. Supportive Care in Cancer. 2023 May;31(5):256

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The Use of Salvage Chemotherapy for Patients with Relapsed Testicular Germ Cell Tumor (GCT) in Canada: A National Survey

Al-Ezzi EM, Zahralliyali A, Hansen AR, Hamilton RJ, Crump M, Kuruvilla J, Wood L, Nappi L, Kollmannsberger CK, North SA, Winquist E, Soulières D, Hotte SJ, Jiang DM. The Use of Salvage Chemotherapy for Patients with Relapsed Testicular Germ Cell Tumor (GCT) in Canada: A National Survey. Current Oncology. 2023 June; 30(7): 6166-6176

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Information Provision, Decision Self-efficacy, and Decisional Conflict in Adopting Health Behaviors Among Patients Treated for Colorectal Cancer

Lee MK, Bryant-Lukosius D. Information Provision, Decision Self-efficacy, and Decisional Conflict in Adopting Health Behaviors Among Patients Treated for Colorectal Cancer: A Cross-sectional Study. Cancer Nurs. 2023 Jan-Feb 01;46(1):45-56. doi: 10.1097/NCC.0000000000001040. Epub 2021 Nov 24. PMID: 34817417.

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Doxycycline-Induced Changes in Circulating MMP or TIMP2 Levels Are Not Associated with Skeletal-Related Event-Free or Overall Survival in Patients with Bone Metastases from Breast Cancer

Zhao H, Pond G, Simos D, Wang Z, Robertson S, Singh G, Vandermeer L, Clemons M, Addison CL. Doxycycline-Induced Changes in Circulating MMP or TIMP2 Levels Are Not Associated with Skeletal-Related Event-Free or Overall Survival in Patients with Bone Metastases from Breast Cancer. Cancers (Basel). 2023 Jan 17;15(3):571.

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Impact of a Training Program on Oncology Nurses’ Confidence in the Provision of Self-Management Support and 5As Behavioral Counseling Skills

Howell D, McGowan P, Bryant-Lukosius D, Kirkby R, Powis M, Sherifali D, Kukreti V, Rask S, Krzyzanowska MK. Impact of a Training Program on Oncology Nurses' Confidence in the Provision of Self-Management Support and 5As Behavioral Counseling Skills. Cancers (Basel). 2023 Mar 16;15(6):1811

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Why Is Multiple Sclerosis More Frequent in Women? Role of the Immune System and of Oral and Gut Microbiota

D’Anca M, Buccellato FR, Tartaglia GM, Del Fabbro M, Muti P, Scarpini E, Galimberti D, Ghezzi L. Why Is Multiple Sclerosis More Frequent in Womn? Role of the Immune System and of Oral and Gut Microbiota. Applied Sciences. 2023; 13(10):588

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HDACi-dependent Microenvironmental Normalization Overcomes Tumor Burden-induced T-cell Exhaustion.

Nguyen A, Brown D, Krishnan R, Bastin D, Deng L, Chen L, Salem O, Walsh SR, Bramson JL, Wan Y. HDACi-dependent Microenvironmental Normalization Overcomes Tumor Burden-induced T-cell Exhaustion. Clin Cancer Res. 2023 Oct 13;29(20):4289-4305.

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CN57 Patients, informal caregivers and healthcare professionals experience in adoptive cell therapies: An experience-based co-design study (EBCD-ACT)

Canova N, Graber N, Corbière T, Bosisio F, Kaufmann A, Bryant-Lukosius D, Eicher M, Colomer-Lahiguera S. CN57 Patients, informal caregivers and healthcare professionals experience in adoptive cell therapies: An experience-based co-design study (EBCD-ACT). Annals of Oncology. Oct 2023, 34: s1242

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Pembrolizumab-induced immune-related sclerosing cholangitis

Liang I, Chu G, Zielinski R. Pembrolizumab Induced Sclerosing Cholangitis: Why You Need a Liver Biopsy. Case Rep Oncol. 2023 Mar 31;16(1):182-187.

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Incidence of second primary malignancies in patients with multiple myeloma receiving anti-CD38 monoclonal antibodies: A systematic review and meta-analysis

Mian A, Naqvi SAA, Ayaz A, Husnain M, Aljama MA, Mohyuddin GR, Koehn K, Mohan M, Bin Riaz I, Chakraborty R. Incidence of second primary malignancies in patients with multiple myeloma receiving anti-CD38 monoclonal antibodies: A systematic review and meta-analysis. Leuk Res. 2023 Aug;131:107324. doi: 10.1016/j.leukres.2023.107324. Epub 2023 May 23. PMID: 37285641.

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Evaluating Oncology Clinical Pathways: What Bar Are We Aiming for?

Ellis PM. Evaluating Oncology Clinical Pathways: What Bar Are We Aiming for? JCO Oncol Pract. 2023 Sep;19(9):692-693. doi: 10.1200/OP.23.00376. Epub 2023 Aug 21. PMID: 37603821.

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Early humoral and cellular responses after bivalent SARS‐CoV‐2 mRNA‐1273.214 vaccination in long‐term care and retirement home residents in Ontario, Canada: An observational cohort study

Breznik JA, Rahim A, Bhakta H, Clare R, Zhang A, Ang J, Stacey HD, Liu LM, Kennedy A, Bilaver L, Hagerman M, Kajaks T, Bramson JL, Nazy I, Miller MS, Costa AP, Bowdish DME; COVID in LTC Investigator Group. Early humoral and cellular responses after bivalent SARS-CoV-2 mRNA-1273.214 vaccination in long-term care and retirement home residents in Ontario, Canada: An observational cohort study. J Med Virol. 2023 Oct;95(10):e29170. doi: 10.1002/jmv.29170. PMID: 37822054.

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Partial Breast Irradiation for Patients With Early-Stage Invasive Breast Cancer or Ductal Carcinoma In Situ: An ASTRO Clinical Practice Guideline (Pract Radiat Oncol. 2024;14:xxx-xxx. Epub ahead of print November 14, 2023.)

Shaitelman SF, Anderson BM, Arthur DW, Bazan JG, Bellon JR, Bradfield L, Coles CE, Gerber NK, Kathpal M, Kim L, Laronga C, Meattini I, Nichols EM, Pierce LJ, Poppe MM, Spears PA, Vinayak S, Whelan T, Lyons JA. Publisher's Note to Partial Breast Irradiation for Patients With Early-Stage Invasive Breast Cancer or Ductal Carcinoma In Situ: An ASTRO Clinical Practice Guideline (Pract Radiat Oncol. 2024;14:xxx-xxx. Epub ahead of print November 14, 2023.). Pract Radiat Oncol. 2023 Nov 18:S1879-8500(23)00301-6. doi: 10.1016/j.prro.2023.11.005. Epub ahead of print. PMID: 37984712.

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The SGLT2 inhibitor canagliflozin suppresses growth and enhances prostate cancer response to radiotherapy

Ali A, Mekhaeil B, Biziotis OD, Tsakiridis EE, Ahmadi E, Wu J, Wang S, Singh K, Menjolian G, Farrell T, Mesci A, Liu S, Berg T, Bramson JL, Steinberg GR, Tsakiridis T. The SGLT2 inhibitor canagliflozin suppresses growth and enhances prostate cancer response to radiotherapy. Commun Biol. 2023 Sep 8;6(1):919. doi: 10.1038/s42003-023-05289-w. PMID: 37684337; PMCID: PMC10491589.

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Overcoming Resistance Mechanisms to Immune Checkpoint Inhibitors: Leveraging the Anti-Tumor Immune Response

Coschi CH, Juergens RA. Overcoming Resistance Mechanisms to Immune Checkpoint Inhibitors: Leveraging the Anti-Tumor Immune Response. Curr Oncol. 2023 Dec 19;31(1):1-23. doi: 10.3390/curroncol31010001. PMID: 38275827; PMCID: PMC10814017.

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Outcomes of patients with advanced non-clear cell renal cell carcinoma treated with first-line immune checkpoint inhibitor therapy

Graham J, Wells JC, Dudani S, Gan CL, Donskov F, Lee J-L, Kollmannsberger CK, Meza L, Beuselinck B, Hansen A, North SA, Bjarnason GA, Sayegh N, Kanesvaran R, Wood LA, Hotte SJ, McKay RR, Choueiri TK, Heng DYC. Outcomes of patients with advanced non-clear cell renal cell carcinoma treated with first-line immune checkpoint inhibitor therapy. European Journal of Cancer. 2022 Aug; 171: 124-132

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Next Wave of Targets in the Treatment of Advanced Renal Cell Carcinoma

Cardenas LM, Deluce JE, Khan S, Gulam O, Vareki SM, Fernandes R, Lalani A-KA. Next Wave of Targets in the Treatment of Advanced Renal Cell Carcinoma. Current Oncology. 2022 Jul 30;29(8):5426-5441.

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Trends in quality indicators of end-of-life care for women with gynecologic malignancies in Ontario, Canada

Mah SJ, Seow H, Schnarr K, Reade CJ, Gayowsky A, Chan KKW, Sinnarajah A. Trends in quality indicators of end-of-life care for women with gynecologic malignancies in Ontario, Canada. Gynecologic Oncology. 2022 Sep 23;S0090-8258(22)01822-4.

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Development, Implementation, and Evaluation of a Distance Learning and Telementoring Program for Cervical Cancer Prevention in Cameroon

Fokom Domgue J, Pande M, Yu R, Manjuh F, Welty E, Welty T, Elit L, Lopez-Varon M, Rodriguez J, Baker E, Dangou JM, Basu P, Plante M, Lecuru F, Randall T, Starr E, Kamgno J, Foxhall L, Waxman A, Hawk E, Schmeler K, Shete S. Development, Implementation, and Evaluation of a Distance Learning and Telementoring Program for Cervical Cancer Prevention in Cameroon. JAMA Netw Open. 2022 Nov 1;5(11):e2240801.

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Predicting Severity of Head Collision Events in Elite Soccer Using Preinjury Data: A Machine Learning Approach

Tarzi G, Tarzi C, Saha A, Cusimano MD. Predicting Severity of Head Collision Events in Elite Soccer Using Preinjury Data: A Machine Learning Approach. Clin J Sport Med. 2023 Mar 1;33(2):165-171.

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Magnetic Resonance Imaging–Targeted Versus Systematic Prostate Biopsies: 2-year Follow-up of a Prospective Randomized Trial (PRECISE)

Klotz L, Chin J, Black PC, Finelli A, Anidjar M, Machado A, Levental M, Ghai S, Chang SD, Patel C, Kassam Z, Loblaw A, Kebabdjian M, Pond G, Haider MA. Magnetic Resonance Imaging-Targeted Versus Systematic Prostate Biopsies: 2-year Follow-up of a Prospective Randomized Trial (PRECISE). Eur Urol Oncol. 2024 Jun;7(3):456-461. doi: 10.1016/j.euo.2023.09.013. Epub 2023 Oct 12. PMID: 37838556.

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Perspectives on geriatric oncology research presented at the 2023 American Society of Hematology Annual Meeting: Young International Society of Geriatric Oncology report

Abdallah M, Akhtar OS, Major A, Mian H, Tsang M, Torka P. Perspectives on geriatric oncology research presented at the 2023 American Society of Hematology Annual Meeting: Young International Society of Geriatric Oncology report. J Geriatr Oncol. 2024 Jun;15(5):101762. doi: 10.1016/j.jgo.2024.101762. Epub 2024 Apr 11. PMID: 38609752.

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Are We Consulting, Sharing Care, or Taking Over? A Conceptual Framework

Pereira, J., Klinger, C., Seow, H., Marshall, D., & Herx, L. (2024). Are We Consulting, Sharing Care, or Taking Over? A Conceptual Framework. Palliative medicine reports, 5(1), 104–115. https://doi.org/10.1089/pmr.2023.0079

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Combined TP53 status in tumor-free resection margins and circulating microRNA profiling predicts the risk of locoregional recurrence in head and neck cancer

Ganci, F., Allegretti, M., Frascolla, C., Spinella, F., Rollo, F., Sacconi, A., Valentina, P., Palcau, A. C., Manciocco, V., Vescovo, M., Cotroneo, E., Blandino, F., Benevolo, M., Covello, R., Muti, P., et al. (2024). Combined TP53 status in tumor-free resection margins and circulating microRNA profiling predicts the risk of locoregional recurrence in head and neck cancer. Biomarker research, 12(1), 32. https://doi.org/10.1186/s40364-024-00576-y

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Access to Oncology Medicines in Canada: Consensus Forum for Recommendations for Improvement †

Sehdev, S. R., Rawson, N. S. B., Aseyev, O. I., Buick, C. J., Butler, M. O., Edwards, S., Gill, S., Gotfrit, J. M., Hsia, C. C., Juergens, R. A., et al. (2024). Access to Oncology Medicines in Canada: Consensus Forum for Recommendations for Improvement. Current oncology (Toronto, Ont.), 31(4), 1803–1816. https://doi.org/10.3390/curroncol31040136

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The Significance of Thyroid Hormone Receptors in Breast Cancer: A Hypothesis-Generating Narrative Review

Quan T, Cockburn J, Dhesy-Thind S, Bane A, Leong H, Geleff C, Devion C, Ajel N, Jerzak KJ. The Significance of Thyroid Hormone Receptors in Breast Cancer: A Hypothesis-Generating Narrative Review. Curr Oncol. 2024 Apr 23;31(5):2364-2375. doi: 10.3390/curroncol31050176. PMID: 38785457; PMCID: PMC11119174.

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Outcomes for International Metastatic Renal Cell Carcinoma Database Consortium Prognostic Groups in Contemporary First-line Combination Therapies for Metastatic Renal Cell Carcinoma

Ernst MS, Navani V, Wells JC, Donskov F, Basappa N, Labaki C, Pal SK, Meza L, Wood LA, Ernst DS, Szabados B, McKay RR, Parnis F, Suarez C, Yuasa T, Lalani A-K, Alva A, Bjarnason GA, Choueiri TK, Heng DYC. Outcomes for International Metastatic Renal Cell Carcinoma Database Consortium Prognostic Groups in Contemporary First-line Combination Therapies for Metastatic Renal Cell Carcinoma. European Urology. 2023 July; 84(1) 109-116.

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Three-Year Outcomes Following Permissive Cardiotoxicity in Patients on Trastuzumab.

Zhou S, Cirne F, Chow J, Zereshkian A, Bordeleau L, Dhesy-Thind S, Ellis PM, Mukherjee SD, Aghel N, Leong DP. Three-Year Outcomes Following Permissive Cardiotoxicity in Patients on Trastuzumab. The Oncologist. 2023 May.

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Education modalities for serious illness communication training: A scoping review on the impact on clinician behavior and patient outcomes.

Lavecchia M, Myers J, Bainbridge D, Incardona N, Levine O, Steinberg L, Schep D, Vautour J, Kumar SJ, Seow H. Education modalities for serious illness communication training: A scoping review on the impact on clinician behavior and patient outcomes. Palliative Medicine. 2023 July.

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Surgical, Radiation, and Systemic Treatments of Patients With Thymic Epithelial Tumors: A Systematic Review

Falkson CB, Vella ET, Ellis PM, Maziak DE, Ung YC, Yu E. Surgical, Radiation, and Systemic Treatments of Patients With Thymic Epithelial Tumors: A Systematic Review. J Thorac Oncol. 2023 Mar;18(3):299-312. doi: 10.1016/j.jtho.2022.10.016. Epub 2022 Nov 4. PMID: 36343922.

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Use of population-based electronic databases for the identification of patients with synchronous colorectal cancer and liver metastases potentially eligible for a surgical trial

Serrano PE, Griffiths CD, Fabbro M, Jibrael S, Levine M, Bhandari M, Parpia S, Simunovic M. Use of population-based electronic databases for the identification of patients with synchronous colorectal cancer and liver metastases potentially eligible for a surgical trial. Can J Surg. 2023 Feb 2;66(1):E52-E58

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Implementation of a Web-Based Communication System for Primary Care Providers and Cancer Specialists

Petrovic B, Bender JL, Liddy C, Afkham A, McGee SF, Morgan SC, Segal R, O’Brien MA, Julian JA, Sussman J, Urquhart R, Fitch M, Schneider ND, Grunfeld E. Implementation of a Web-Based Communication System for Primary Care Providers and Cancer Specialists. Current Oncology. 2023; 30(3):3537-3548.

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Activated KRAS, polyamines, iASPP and TME: a multiple liaison in pancreatic cancer

Blandino G. Activated KRAS, polyamines, iASPP and TME: a multiple liaison in pancreatic cancer. Cell Death Differ. 2023 Jun;30(6):1615-1617

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Canagliflozin mediates tumor suppression alone and in combination with radiotherapy in non?small cell lung cancer (NSCLC) through inhibition of HIF?1?

Biziotis OD, Tsakiridis EE, Ali A, Ahmadi E, Wu J, Wang S, Mekhaeil B, Singh K, Menjolian G, Farrell T, Abdulkarim B, Sur RK, Mesci A, Ellis P, Berg T, Bramson JL, Muti P, Steinberg GR, Tsakiridis T. Canagliflozin mediates tumor suppression alone and in combination with radiotherapy in non-small cell lung cancer (NSCLC) through inhibition of HIF-1?. Mol Oncol. 2023 Nov;17(11):2235-2256.

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Phase 1 Dose-Escalation Study of the Safety and Pharmacokinetics of AGS15E Monotherapy in Patients With Metastatic Urothelial Carcinoma.

Petrylak DP, Eigl BJ, George S, Heath EI, Hotte SJ, Chism DD, Nabell LM, Picus J, Cheng SY, Appleman LJ, Sonpavde GP, Morgans AK, Pourhosseini P, Wu R, Standley L, Croitoru R, Yu EY. Phase 1 Dose-Escalation Study of the Safety and Pharmacokinetics of AGS15E Monotherapy in Patients With Metastatic Urothelial Carcinoma. Clin Cancer Res. 2023 Oct 20.

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PDP1 is a key metabolic gatekeeper and modulator of drug resistance in FLT3-ITD-positive acute myeloid leukemia

Alshamleh I, Kurrle N, Makowka P, Bhayadia R, Kumar R, Süsser S, Seibert M, Ludig D, Wolf S, Koschade SE, Stoschek K, Kreitz J, Fuhrmann DC, Toenges R, Notaro M, Comoglio F, Schuringa JJ, Berg T, Brüne B, Krause DS, Klusmann J-H, Oellerich T, Schnütgen F, Schwalbe H, Serve H. PDP1 is a key metabolic gatekeeper and modulator of drug resistance in FLT3-ITD-positive acute myeloid leukemia. Leukemia. 2023 Nov 37(12):1-16

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Trials using composite outcomes neglect the presence of competing risks: a methodological survey of cardiovascular studies

Kim H, Shahbal H, Parpia S, Averbuch T, Van Spall HGC, Thabane L, Ma J. Trials using composite outcomes neglect the presence of competing risks: a methodological survey of cardiovascular studies. J Clin Epidemiol. 2023 Aug;160:1-13. doi: 10.1016/j.jclinepi.2023.05.015. Epub 2023 May 27. PMID: 37245700.

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Enhanced Recovery After Surgery (ERAS) protocols following emergency intra-abdominal surgery: A systematic review and meta-analysis protocol

McKechnie T, Parpia S, Bhandari M, Dionne JC, Eskicioglu C. Enhanced Recovery After Surgery (ERAS) protocols following emergency intra-abdominal surgery: A systematic review and meta-analysis protocol. PLoS One. 2023 Sep 8;18(9):e0291140. doi: 10.1371/journal.pone.0291140. PMID: 37682876; PMCID: PMC10490890.

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Final Results from a Prospective Randomized Pilot Trial of Stereotactic Body Radiation Therapy vs. Radiofrequency Ablation for the Management of Small Renal Masses (RADSTER)

Swaminath, A., Cassim, R., Millan, B., Mironov, O., Ahir, P., Tajzler, C., Hoogenes, J., Quan, K., Matsumoto, E., & Kapoor, A. (2023). Final results from a prospective randomized pilot trial of stereotactic body radiation therapy vs. radiofrequency ablation for the management of small renal masses (RADSTER). International Journal of Radiation Oncology*Biology*Physics, 117(2). https://doi.org/10.1016/j.ijrobp.2023.06.402

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Effective and safe regional node irradiation in early breast cancer

Levine MN. Effective and safe regional node irradiation in early breast cancer. Lancet. 2023 Nov 25;402(10416):1943-1945. doi: 10.1016/S0140-6736(23)01614-8. Epub 2023 Nov 3. PMID: 37931630.

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Real-world results of autologous stem cell transplantation in newly diagnosed multiple myeloma: a report from the Canadian Myeloma Research Group database

Côté J, LeBlanc R, Mian H, Chu MP, McCurdy A, Masih-Khan E, Su J, Jimenez-Zepeda VH, Song K, Louzada M, White D, Sebag M, Reiman A, Stakiw J, Kotb R, Bergstrom D, Aslam M, Kaedbey R, Venner CP, Gul E, Reece D. Real-world results of autologous stem cell transplantation in newly diagnosed multiple myeloma: a report from the Canadian Myeloma Research Group database. Blood Cancer J. 2023 Sep 5;13(1):137. doi: 10.1038/s41408-023-00905-8. PMID: 37669949; PMCID: PMC10480201.

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Pharmacological class effects of anticancer drugs: opportunities for decreasing healthcare spending

Daniel A Goldstein, Leonard B Saltz, Gregory R Pond, Ian F Tannock - Pharmacological class effects of anticancer drugs: opportunities for decreasing healthcare spending: BMJ Oncology 2024;3:e000287.

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Systematically higher Ki67 scores on core biopsy samples compared to corresponding resection specimen in breast cancer: a multi-operator and multi-institutional study

Acs B, Leung SCY, Kidwell KM, Arun I, Augulis R, Badve SS, Bai Y, Bane AL, Bartlett JMS, Bayani J, Bigras G, Blank A, Buikema H, Chang MC, Dietz RL, Dodson A, Fineberg S, Focke CM, Gao D, Gown AM, Gutierrez C, Hartman J, Kos Z, Lænkholm A-V, Laurinavicius A, Levenson RM, Mahboubi-Ardakani R, Mastropasqua MG, Nofech-Mozes S, Osborne CK, Penault-Llorca FM, Piper T, Quintayo MA, Rau TT, Reinhard S, Robertson S, Salgado R, Sugie T, van der Vegt B, Viale G, Zabaglo LA, Hayes DF, Dowsett M, Nielsen TO, Rimm DL. Systematically higher Ki67 scores on core biopsy samples compared to corresponding resection specimen in breast cancer: a multi-operator and multi-institutional study. Modern Pathology. 2022 Oct; 35(10): 1362-1369

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Identifying Breast Cancer Recurrence in Administrative Data: Algorithm Development and Validation

Holloway CMB, Shabestari O, Eberg M, Forster K, Murray P, Green B, Esensoy AV, Eisen A, Sussman J. Identifying Breast Cancer Recurrence in Administrative Data: Algorithm Development and Validation. Current Oncology. 2022 Jul 28;29(8):5338-5367.

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Low-Dose Hemibody Radiation, a Treatment Option for Recurrent Prostate Cancer: A Phase 2 Single-Arm Trial

Low-Dose Hemibody Radiation, a Treatment Option for Recurrent Prostate Cancer: A Phase 2 Single-Arm Trial. Advances in Radiation Oncology. 2022 Sep 10;8(1):101066.

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FRACTION-RCC: nivolumab plus ipilimumab for advanced renal cell carcinoma after progression on immuno-oncology therapy

Choueiri TK, Kluger H, George S, Tykodi SS, Kuzel TM, Perets R, Nair S, Procopio G, Carducci MA, Castonguay V, Folefac E, Lee CH, Hotte SJ, Miller WH Jr, Saggi SS, Lee CW, Desilva H, Bhagavatheeswaran P, Motzer RJ, Escudier B. FRACTION-RCC: nivolumab plus ipilimumab for advanced renal cell carcinoma after progression on immuno-oncology therapy. J Immunother Cancer. 2022 Nov;10(11):e005780.

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A new platform for post-marketing surveillance and real-world evidence data collection for substance-based medical devices

Cioeta R, Cossu A, Giovagnoni E, Rigoni M, Muti P. A new platform for post-marketing surveillance and real-world evidence data collection for substance-based medical devices. Frontiers in Drug Safety and Regulation. 2022. 2;992359

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Long-Term Analysis of NRG Oncology RTOG 0415: A Randomized Phase III Noninferiority Study Comparing Two Fractionation Schedules in Patients With Low-Risk Prostate Cancer.

Lee WR, Dignam JJ, Amin MB, Bruner DW, Low D, Swanson GP, Shah AB, D'Souza D, Michalski JM, Dayes IS, et al. Long-Term Analysis of NRG Oncology RTOG 0415: A Randomized Phase III Noninferiority Study Comparing Two Fractionation Schedules in Patients With Low-Risk Prostate Cancer. J Clin Oncol. 2024 May 17:JCO2302445. doi: 10.1200/JCO.23.02445. Epub ahead of print. PMID: 38759121.

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Characterization of Responses to Lenvatinib plus Pembrolizumab in Patients with Advanced Renal Cell Carcinoma at the Final Prespecified Survival Analysis of the Phase 3 CLEAR Study

Motzer RJ, Choueiri TK, Hutson T, Young Rha S, Puente J, Lalani AA, Winquist E, Eto M, Basappa NS, Tannir NM, Vaishampayan U, Bjarnason GA, Oudard S, Grünwald V, Burgents J, Xie R, McKenzie J, Powles T. Characterization of Responses to Lenvatinib plus Pembrolizumab in Patients with Advanced Renal Cell Carcinoma at the Final Prespecified Survival Analysis of the Phase 3 CLEAR Study. Eur Urol. 2024 Apr 5:S0302-2838(24)02234-6. doi: 10.1016/j.eururo.2024.03.015. Epub ahead of print. PMID: 38582713.

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Virtual follow‐up care among breast and prostate cancer patients during and beyond the COVID‐19 pandemic: Association with distress

Bender, J. L., Scruton, S., Wong, G., Abdelmutti, N., Berlin, A., Easley, J., Liu, Z. A., McGee, S., Rodin, D., Sussman, J., & Urquhart, R. (2024). Virtual follow-up care among breast and prostate cancer patients during and beyond the COVID-19 pandemic: Association with distress. Cancer medicine, 13(4), e6948. https://doi.org/10.1002/cam4.6948

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The REthinking Clinical Trials Program Retreat 2023: Creating Partnerships to Optimize Quality Cancer Care

Beltran-Bless, A. A., Clemons, M., Vandermeer, L., El Emam, K., Ng, T. L., McGee, S., Awan, A. A., Pond, G., Renaud, J., Barton, G., Hutton, B., & Savard, M. F. (2024). The REthinking Clinical Trials Program Retreat 2023: Creating Partnerships to Optimize Quality Cancer Care. Current oncology (Toronto, Ont.), 31(3), 1376–1388. https://doi.org/10.3390/curroncol31030104

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PREscribing preoperative weight loss prior to major non-bariatric abdominal surgery for patients with Elevated weight: Patient and Provider Survey Protocols (PREPARE surveys)

McKechnie, T., Saddik, M., Doumouras, A., Eskicioglu, C., Parpia, S., & Bhandari, M. (2024). PREscribing preoperative weight loss prior to major non-bariatric abdominal surgery for patients with Elevated weight: Patient and Provider Survey Protocols (PREPARE surveys). PloS one, 19(4), e0302482. https://doi.org/10.1371/journal.pone.0302482

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Perspectives on shorter durations of anti-HER2 therapy in early-stage HER2-positive breast cancer: a patient survey

Bradbury M, Savard MF, Stober C, Clemons L, Clemons M, Hilton J, Pond G, Vandermeer L, McGee SF. Perspectives on shorter durations of anti-HER2 therapy in early-stage HER2-positive breast cancer: a patient survey. Breast Cancer Res Treat. 2024 Apr 25. doi: 10.1007/s10549-024-07302-0. Epub ahead of print. PMID: 38664288.

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Management of Patients with Cardiovascular Implantable Electronic Devices Undergoing Radiation Therapy: A National Survey of Canadian Multidisciplinary Radiation Oncology Professionals

Safavi AH, Louie AV, Elzibak AH, Warner A, Donovan EK, Detsky JS. Management of Patients with Cardiovascular Implantable Electronic Devices Undergoing Radiation Therapy: A National Survey of Canadian Multidisciplinary Radiation Oncology Professionals. Advances in Radiation Oncology. 2023 July; 8(4) 101-184.

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Cost-utility analysis of a multispecialty interprofessional team dementia care model in Ontario, Canada

Wong WWL, Lee L, Walker S, Lee C, Patel T, Hillier LM, Costa AP, Sinha SK. Cost-utility analysis of a multispecialty interprofessional team dementia care model in Ontario, Canada. BMJ Open. 2023 April;13(4) : 648

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Optimizing Treatment Selection in Advanced Renal Cell Carcinoma via IMDC Risk Group Stratification

Hird AE, Chavarriaga J, Lalani A-KA, Wallis CJD. Optimizing Treatment Selection in Advanced Renal Cell Carcinoma via IMDC Risk Group Stratification. European Urology. 2023 July; 2838(23)

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The European Society of Cardiology Cardio-Oncology Guidelines Evidence Base, Actionability, and Relevance to Clinical Practice

Leong DP, Mukherjee SD. The European Society of Cardiology Cardio-Oncology Guidelines. J Am Coll Cardiol CardioOnc. 2023 Feb;5 (1);137–140.

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Oncologic Outcomes of Surgically Treated Cervical Cancer with No Residual Disease on Hysterectomy Specimen: A 4C (Canadian Cervical Cancer Collaborative) Working Group Study

Aubrey C, Pond GR, Helpman L, Vicus D, Elit L, Plante M, Lau S, Kwon JS, Altman AD, Willows K, Feigenberg T, Sabourin J, Samouelian V, Bernard L, Cockburn N, Saunders NB, Piedimonte S, Teo-Fortin LA, Kim SR, Sadeq N, Jang JH, Shamiya S, Nelson G. Oncologic Outcomes of Surgically Treated Cervical Cancer with No Residual Disease on Hysterectomy Specimen: A 4C (Canadian Cervical Cancer Collaborative) Working Group Study. Curr Oncol. 2023 Feb 6;30(2):1977-1985.

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Regularly scheduled physical examinations and the detection of breast cancer recurrences

Beltran-Bless AA, Alshamsan B, Alzahrani MJ, Hilton J, Baines KA, Samuel V, Pond GR, Vandermeer L, Clemons M, Larocque G. Regularly scheduled physical examinations and the detection of breast cancer recurrences. Breast. 2023 Jun;69:274-280.

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A Two-Center Experience: The Impact of COVID-19 on Two Brachytherapy Programs in Ontario – Virtual Care, Service Suspension and Radiation Therapy Workflow

Chan K, Timotin E, Chung P, Han K, Milosevic M, Schnarr K, Sur R, Bosche J, Harnett N. A two-center experience: The impact of COVID-19 on two brachytherapy programs in Ontario - virtual care, service suspension and radiation therapy workflow. J Med Imaging Radiat Sci. 2023 Sep;54(3):436-445. doi: 10.1016/j.jmir.2023.05.043. Epub 2023 May 29. PMID: 37357051; PMCID: PMC10289124.

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Current and Future Treatment Options in the Management of Stage III NSCLC

Li Y, Juergens RA, Finley C, Swaminath A. Current and Future Treatment Options in the Management of Stage III NSCLC. J Thorac Oncol. 2023 Nov;18(11):1478-1491

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Transitional care from hospital to home: how to target the right population?

Michalski-Monnerat C, Jacquot-Pegeot ML, Rochat S, Schmid MC, Maillat Roth S, Chevrey N, Toledano Y, Jeannot JG, Donzé J, Bryant-Lukosius D, Mabire C. Soins de transition entre l’hôpital et le domicile: pour quels patient-es ? [Transitional care from hospital to home: how to target the right population?]. Rev Med Suisse. 2023 Oct 25;19(847):2021-2025..

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Progression-Free Survival as a Surrogate Endpoint of Overall Survival in Patients with Locally Advanced Non-Small Cell Lung Cancer Treated with Chemoradiotherapy: Trial-Level Meta-Analysis and Individual-Level Analysis of NRG/RTOG 0617 and PROCLAIM

Hu C, Miccio JA, Dignam JJ, Paulus R, Liu C, Skinner HD, et al. Progression-free survival as a surrogate endpoint of overall survival in patients with locally advanced non-small cell lung cancer treated with chemoradiotherapy: trial-level meta-analysis and individual-level analysis of nrg/rtog 0617 and proclaim. International Journal of Radiation Oncology . 2023 Oct 1 ;117(2):S128.

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Management of metastatic head and neck Cancer: An all-in, kitchen-sink Approach?

Yeung C, Meyers BM, Kartolo A. Management of metastatic head and neck Cancer: An all-in, kitchen-sink Approach? Oral Oncol. 2023 Aug;143:106444. doi: 10.1016/j.oraloncology.2023.106444. Epub 2023 Jun 17. PMID: 37336178.

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Fractionated Stereotactic Radiation for Central Nervous System Lymphoma: Retrospective Analysis of Initial Cases

Schep DG, Mir T, Fraser GAM, Greenspoon JN. Fractionated Stereotactic Radiation for Central Nervous System Lymphoma: Retrospective Analysis of Initial Cases. Curr Oncol. 2023 Sep 20;30(9):8602-8611. doi: 10.3390/curroncol30090624. PMID: 37754539; PMCID: PMC10530215.

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Evaluation of Volumetric Response Assessment from Stereotactic Ablative Radiotherapy (SABR) for Renal Cell Carcinoma (RCC)

Schep, D., Dayes, I., Lukka, H., Quan, K., Kapoor, A., Vansantvoort, J., Chow, T., & Swaminath, A. (2023). Evaluation of volumetric response assessment from stereotactic ablative radiotherapy (SABR) for renal cell carcinoma (RCC). International Journal of Radiation Oncology*Biology*Physics, 117(2). https://doi.org/10.1016/j.ijrobp.2023.06.1603

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Physical Activity During Adolescence and Early-adulthood and Ovarian Cancer Among Women with a BRCA1 or BRCA2 Mutation

Guyonnet E, Kim SJ, Xia YY, Giannakeas V, Lubinski J, Randall Armel S, Eisen A, Bordeleau L, et al. Physical Activity During Adolescence and Early-adulthood and Ovarian Cancer Among Women with a BRCA1 or BRCA2 Mutation. Cancer Res Commun. 2023 Nov 28;3(11):2420-2429. doi: 10.1158/2767-9764.CRC-23-0223. PMID: 38019076; PMCID: PMC10683556.

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Implementing palliative care education into primary care practice: a qualitative case study of the CAPACITI pilot program

Matthew M, Bainbridge D, Bishop V, Sinding C, Winemaker S, Kilbertus F, Kortes-Miller K, Seow H. Implementing palliative care education into primary care practice: a qualitative case study of the CAPACITI pilot program. BMC Palliat Care. 2023 Sep 28;22(1):143. doi: 10.1186/s12904-023-01265-7. PMID: 37759200; PMCID: PMC10537555.

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Teclistamab in Relapsed or Refractory Multiple Myeloma

Cliff E, Mian H, Mohyuddin G. N Engl J Med. 2022 Nov 3;387(18):1721-1722.

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MALAT1-dependent hsa_circ_0076611 regulates translation rate in triple-negative breast cancer

Turco C, Esposito G, Iaiza A, Goeman F, Benedetti A, Gallo E, Daralioti T, Perracchio L, Sacconi A, Pasanisi P, Muti P, Pulito C, Strano S, Ianniello Z, Fatica A, Forcato M, Fazi F, Blandino G, Fontemaggi G. MALAT1-dependent hsa_circ_0076611 regulates translation rate in triple-negative breast cancer. Communications Biology. 2022 Jun; 5(1): 598

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Quality of end?of?life care in multiple myeloma: A 13?year analysis of a population?based cohort in Ontario, Canada

Mohyuddin GR, Sinnarajah A, Gayowsky A, Chan KKW, Seow H, Mian H. Quality of end?of?life care in multiple myeloma: A 13?year analysis of a population?based cohort in Ontario, Canada. British Journal of Haematology. 2022 Dec;199(5):688-695.

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Desmoplastic small round cell tumor involving the uterine cervix: The first reported case in the literature, and brief review of gynecologic presentations

Kapoor R, Sur M, Kagoma YK, Schnarr K, Zbuk K, Nguyen JMV. Desmoplastic small round cell tumor involving the uterine cervix: The first reported case in the literature, and brief review of gynecologic presentations. Gynecol Oncol Rep. 2022 Oct 7;44:101079.

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The status of surgical margins in relation to the type of surgical approach in the management of early-stage cervical cancer: Canadian Cervical Cancer Collaborative (4C) study (533)

The status of surgical margins in relation to the type of surgical approach in the management of early-stage cervical cancer: Canadian Cervical Cancer Collaborative (4C) study (533). Gynecologic Oncology. 2022 Aug; 166;261

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Effectiveness and tolerability of Poliprotect, a natural mucosal protective agent for gastroesophageal reflux disease and dyspepsia: Surveys from patients, physicians, and pharmacists

Cioeta R, Muti P, Rigoni M, Morlando L, Siragusa F, Cossu A, Giovagnoni E. Effectiveness and tolerability of Poliprotect, a natural mucosal protective agent for gastroesophageal reflux disease and dyspepsia: Surveys from patients, physicians, and pharmacists. Frontiers in Drug Safety and Regulation. 2022 Oct; 2; 959831

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ASO Visual Abstract: Immigration Status and Breast Cancer Surgery Quality of Care Metrics: A Population-Level Analysis

Parvez, E., Bogach, J., Kirkwood, D. et al. ASO Visual Abstract: Immigration Status and Breast Cancer Surgery Quality of Care Metrics: A Population-Level Analysis. Ann Surg Oncol (2024). https://doi.org/10.1245/s10434-024-15376-9

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Advanced Practice Nurses and Their Roles in Swiss Cancer Care: A Cross-Sectional Study

Geese F, Bryant-Lukosius D, Zwakhalen S, Hahn S. Advanced Practice Nurses and Their Roles in Swiss Cancer Care: A Cross-Sectional Study. Semin Oncol Nurs. 2024 Jun;40(3):151626. doi: 10.1016/j.soncn.2024.151626. Epub 2024 Apr 18. PMID: 38641521.

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Socioeconomic Status, Palliative Care, and Death at Home Among Patients With Cancer Before and During COVID-19

Iqbal, J., Moineddin, R., Fowler, R. A., Krzyzanowska, M. K., Booth, C. M., Downar, J., Lau, J., Le, L. W., Rodin, G., Seow, H., Tanuseputro, P., Earle, C. C., Quinn, K. L., Hannon, B., & Zimmermann, C. (2024). Socioeconomic Status, Palliative Care, and Death at Home Among Patients With Cancer Before and During COVID-19. JAMA network open, 7(2), e240503. https://doi.org/10.1001/jamanetworkopen.2024.0503

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Evaluating Wall-Mounted Prompts to Facilitate Physical Activity-Related Discussion between Individuals with Cancer and Oncology Health Care Providers: A Pre-post Survey Study

Smith-Turchyn, J., Mukherjee, S. D., Tomasone, J. R., Fong, A. J., Nayiga, B. K., Ball, E., Stouth, D. W., & Sabiston, C. M. (2024). Evaluating Wall-Mounted Prompts to Facilitate Physical Activity-Related Discussion between Individuals with Cancer and Oncology Health Care Providers: A Pre-post Survey Study. Physiotherapy Canada. Physiotherapie Canada, 76(1), 34–45. https://doi.org/10.3138/ptc-2023-0046

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Pyroptosis activates conventional type I dendritic cells to mediate the priming of highly functional anticancer T cells

Inkol, J. M., Westerveld, M. J., Verburg, S. G., Walsh, S. R., Morrison, J., Mossman, K. L., Worfolk, S. M., Kallio, K. L., Phippen, N. J., Burchett, R., Wan, Y., Bramson, J., & Workenhe, S. T. (2024). Pyroptosis activates conventional type I dendritic cells to mediate the priming of highly functional anticancer T cells. Journal for immunotherapy of cancer, 12(4), e006781. https://doi.org/10.1136/jitc-2023-006781

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Identification of a Patient Suitable for CAR-T Cell Therapy in the Outpatient Setting: A Vodcast and Case Example

Foley R, Kuruvilla J. Identification of a Patient Suitable for CAR-T Cell Therapy in the Outpatient Setting: A Vodcast and Case Example. Oncol Ther. 2024 Apr 25. doi: 10.1007/s40487-024-00272-9. Epub ahead of print. PMID: 38662113.

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First Line Treatment of Newly Diagnosed Transplant Ineligible Multiple Myeloma: Recommendations from the Canadian Myeloma Research Group Consensus Guideline Consortium

Côté J, Kotb R, Bergstrom DJ, LeBlanc R, Mian HS, Othman I, Louzada ML. First Line Treatment of Newly Diagnosed Transplant Ineligible Multiple Myeloma: Recommendations from the Canadian Myeloma Research Group Consensus Guideline Consortium. Clinical Lymphoma Myeloma & Leukemia. 2023 May; 23(5) 340-354.

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Quality of anticoagulant control and patient experience associated with long-term warfarin in Canadian patients with non-valvular atrial fibrillation: A multicentre, prospective study

Selby R, Kaus L, Sealey F, Koo M, Parpia S, Chan B, Seung SJ, Bradley C, Strauss R, Mittmann N. Quality of anticoagulant control and patient experience associated with long-term warfarin in Canadian patients with non-valvular atrial fibrillation: A multicenter, prospective study. PLOS ONE. 2023;18(4)" 284

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The Judicious Use of Stereotactic Ablative Radiotherapy in the Primary Management of Localized Renal Cell Carcinoma

Barbour AB, Kirste S, Grosu A-L, Siva S, Louie AV, Onishi H, Swaminath A, Teh BS, Psutka SP, Weg ES, Chen JJ, Zeng J, Gore JL, Hall E, Liao JJ, Correa RJM, Lo SS. The Judicious Use of Stereotactic Ablative Radiotherapy in the Primary Management of Localized Renal Cell Carcinoma. Cancers. 2023 July; 15(14): 3672

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Evaluating the impact of early identification of asymptomatic brain metastases in metastatic renal cell carcinoma

Parmar A, Ghosh S, Sahgal A, Lalani AA, Hansen AR, Reaume MN, Wood L, Basappa NS, Heng DYC, Graham J, Kollmannsberger C, Soulières D, Breau RH, Tanguay S, Kapoor A, Pouliot F, Bjarnason GA. Evaluating the impact of early identification of asymptomatic brain metastases in metastatic renal cell carcinoma. Cancer Rep (Hoboken). 2023 Mar;6(3):e1763. doi: 10.1002/cnr2.1763. Epub 2022 Dec 14. PMID: 36517084; PMCID: PMC10026314.

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In Response to Morgan et al. and Li et al.

Goldberg M, McGale P, Whelan TJ. In Response to Morgan et al. and Li et al. Int J Radiat Oncol Biol Phys. 2023 Mar 15;115(4):1012-1013

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Brief Report: Canadian Cancer Trials Group IND.227: A Phase 2 Randomized Study of Pembrolizumab in Patients With Advanced Malignant Pleural Mesothelioma (NCT02784171)

Piccirillo MC, Chu Q, Bradbury P, Tu W, Coschi CH, Grosso F, Florescu M, Mencoboni M, Goffin JR, Pagano M, Ciardiello F, Cecere FL, Vincent M, Ferrara R, Dawe DE, Hao D, Lee CW, Morabito A, Gridelli C, Cavanna L, Iqbal M, Blais N, Leighl NB, Wheatley-Price P, Tsao MS, Ugo F, El-Osta H, Gargiulo P, Gaudreau PO, Tu D, Sederias J, Brown-Walker P, Perrone F, Seymour L, Laurie SA. Brief Report: Canadian Cancer Trials Group IND.227: A Phase 2 Randomized Study of Pembrolizumab in Patients With Advanced Malignant Pleural Mesothelioma (NCT02784171). J Thorac Oncol. 2023 Jun;18(6):813-819.

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Corrigendum to methodological approaches for developing, reporting, and assessing evidence-based clinical practice guidelines: a systematic survey [Journal of Clinical Epidemiology 146 (2022) 77-85]

Yao X, Xia J, Jin Y, Shen Q, Wang Q, Zhu Y, McNair S, Sussman J, Wang Z, Florez ID, Zeng XT, Brouwers M. Corrigendum to methodological approaches for developing, reporting, and assessing evidence-based clinical practice guidelines: a systematic survey [Journal of Clinical Epidemiology 146 (2022) 77-85]. J Clin Epidemiol. 2023 Jul;159:354-355. doi: 10.1016/j.jclinepi.2023.04.003. Epub 2023 Jun 9. Erratum for: J Clin Epidemiol. 2022 Jun;146:77-85. PMID: 37302874.

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Discrete-Choice Experiment to Understand the Preferences of Patients with Hormone-Sensitive Prostate Cancer in the USA, Canada, and the UK

Gonzalez JM, Ganguli A, Morgans AK, Tombal BF, Hotte SJ, Suzuki H, Bhadauria H, Oh M, Scales CD Jr, Wallace MJ, Yang JC, George DJ. Discrete-Choice Experiment to Understand the Preferences of Patients with Hormone-Sensitive Prostate Cancer in the USA, Canada, and the UK. Patient. 2023 Nov;16(6):607-623.

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Radiotherapy for Liver Cancer: An International Multi-Centre Pooled Analysis of 925 Cases

Chow R, Biswas T, Liu H, Pryor DI, Chu W, Swaminath A, Chung HT, Schellenberg D, Grindrod N, Lee YY, Gaede S, Sachdeva R, Lock MI. Radiotherapy for Liver Cancer: An International Multi-Centre Pooled Analysis of 925 Cases. International Journal of radiation Oncology. Oct 2023: 1172(2)

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Enhanced recovery after surgery protocols following emergency intra-abdominal surgery: a systematic review and meta-analysis

McKechnie T, Tessier L, Archer V, Park L, Cohen D, Levac B, Parpia S, Bhandari M, Dionne J, Eskicioglu C. Enhanced recovery after surgery protocols following emergency intra-abdominal surgery: a systematic review and meta-analysis. Eur J Trauma Emerg Surg. 2023 Nov 20. doi: 10.1007/s00068-023-02387-6. Epub ahead of print. PMID: 37985500.

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Palliative care utilization across health sectors for patients with gynecologic malignancies in Ontario, Canada from 2006 to 2018

Mah SJ, Carter Ramirez DM, Eiriksson LR, Schnarr K, Gayowsky A, Seow H. Palliative care utilization across health sectors for patients with gynecologic malignancies in Ontario, Canada from 2006 to 2018. Gynecol Oncol. 2023 Aug;175:169-175. doi: 10.1016/j.ygyno.2023.06.016. Epub 2023 Jun 29. PMID: 37392530.

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Trends of Utilization of Systemic Therapies for Metastatic Renal Cell Carcinoma in the Canadian Health Care System

Cardenas LM, Ghosh S, Finelli A, Wood L, Kollmannsberger C, Basappa N, Graham J, Heng D, Bjarnason G, Soulières D, Bossé D, Castonguay V, Saleh R, Tanguay S, Bhindi B, Breau RH, Pouliot F, Lalani AA. Trends of Utilization of Systemic Therapies for Metastatic Renal Cell Carcinoma in the Canadian Health Care System. JCO Glob Oncol. 2023 Sep;9:e2300271. doi: 10.1200/GO.23.00271. PMID: 37992270; PMCID: PMC10681568.

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ctDNA response after pembrolizumab in non-small cell lung cancer: phase 2 adaptive trial results

Anagnostou V, Ho C, Nicholas G, Juergens RA, Sacher A, Fung AS, Wheatley-Price P, Laurie SA, Levy B, Brahmer JR, Balan A, Niknafs N, Avrutin E, Zhu L, Sausen M, Bradbury PA, O'Donnell-Tormey J, Gaudreau PO, Ding K, Dancey J. ctDNA response after pembrolizumab in non-small cell lung cancer: phase 2 adaptive trial results. Nat Med. 2023 Oct;29(10):2559-2569. doi: 10.1038/s41591-023-02598-9. Epub 2023 Oct 9. PMID: 37814061; PMCID: PMC10579094.

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“There’s So Much More Support We Could Have Provided”: Child Life Specialists’ Stories of the Challenges Working in Adult Oncology.

Taneja S, Vanstone M, Lysecki DL, McKean H, Bainbridge D, Sussman J, Molinaro M. "There's So Much More Support We Could Have Provided": Child Life Specialists' Stories of the Challenges Working in Adult Oncology. Qual Health Res. 2023 Nov 30:10497323231215950. doi: 10.1177/10497323231215950. Epub ahead of print. PMID: 38035631.

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MRD negativity: considerations for older adults with multiple myeloma

Mian H, Wildes TM, Venner CP, Fonseca R. MRD negativity: considerations for older adults with multiple myeloma. Blood Cancer J. 2023 Nov 8;13(1):166. doi: 10.1038/s41408-023-00939-y. PMID: 37938551; PMCID: PMC10632351.

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A Systematic Literature Review of Health Utility Values in Breast Cancer

Kaur MN, Yan J, Klassen AF, David JP, Pieris D, Sharma M, Bordeleau L, Xie F. A Systematic Literature Review of Health Utility Values in Breast Cancer. Medical Decision Making. 2022 July; 42(5) 704-719

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Modifiable risk factors for prostate cancer in low- and lower-middle-income countries: a systematic review and meta-analysis

Cirne F, Kappel C, Zhou S, Mukherjee SD, Dehghan M, Petropoulos J-A, Leong DP. Modifiable risk factors for prostate cancer in low- and lower-middle-income countries: a systematic review and meta-analysis. Prostate Cancer and Prostatic Disease. 2022 Sep; 25(3): 453-462

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Radiation doses and fractionation schedules in non-low-risk ductal carcinoma in situ in the breast (BIG 3–07/TROG 07.01): a randomised, factorial, multicentre, open-label, phase 3 study

Chua BH, Link EK, Kunkler IH, Whelan TJ, Westenberg AH, Gruber G, Bryant G, Ahern V, Purohit K, Graham PH, Akra M, McArdle O, O'Brien P, Harvey JA, Kirkove C, Maduro JH, Campbell ID, Delaney GP, Martin JD, Vu TTT, Muanza TM, Neal A, Olivotto IA, investigators BTT. Radiation doses and fractionation schedules in non-low-risk ductal carcinoma in situ in the breast (BIG 3–07/TROG 07.01): a randomised, factorial, multicentre, open-label, phase 3 study. The Lancet. 2022 Aug 6;400(10350):431-440.

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Lung SBRT credentialing in the Canadian OCOG-LUSTRE randomized trial

Swaminath A, Wierzbicki M, Parpia S, Kundapur V, Faria S, Ahmed N, Bujold A, Hirmiz K, Owen T, Leong N, Ramchandar K, Filion E, Lau H, Thompson R, Yaremko B, Gabos Z, Mehiri S, Wright JR, Tsakiridis TK, Cline K, Whelan TJ. Lung SBRT credentialing in the Canadian OCOG-LUSTRE randomized trial. Clin Transl Radiat Oncol. 2022 Oct 13;37:145-152.

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Germline BRCA mutations are associated with an increased likelihood of secondary cytoreductive surgery in ovarian cancer patients (116)

Yfat K, Mariam K, Mario B, Hal H, Dana J, Lina S, Ilan B, Gregory P, Limor H. Germline BRCA mutation carriers are more likely to undergo cytoreductive surgery for relapsed, platinum sensitive, ovarian cancer. Gynecol Oncol. 2022 Sep 22:S0090-8258(22)00574-1.

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Improvement of type 2 diabetes in a bipolar patient after initiation of atypical antipsychotic therapy.

Claro AE, Palanza C, Mazza M, Rizzi A, Tartaglione L, Marano G, Muti Schuenemann GE, Rigoni M, Muti P, Pontecorvi A, Janiri L, Sani G, Pitocco D. Improvement of type 2 diabetes in a bipolar patient after initiation of atypical antipsychotic therapy. Minerva Endocrinol (Torino). 2022 Aug 1.

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Liver Observation Segmentation on Contrast-Enhanced MRI: SAM and MedSAM Performance in Patients With Probable or Definite Hepatocellular Carcinoma.

Saha A, van der Pol CB. Liver Observation Segmentation on Contrast-Enhanced MRI: SAM and MedSAM Performance in Patients With Probable or Definite Hepatocellular Carcinoma. Can Assoc Radiol J. 2024 May 7:8465371241250215. doi: 10.1177/08465371241250215. Epub ahead of print. PMID: 38715248.

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A Future-Oriented Perspective on Advanced Practice Nursing Roles in Cancer Care: Pushing the Boundaries to Promote Innovation and Achieve Equitable, Patient-Centered Care

Bryant-Lukosius D, Pape E, Dowling M. A Future-Oriented Perspective on Advanced Practice Nursing Roles in Cancer Care: Pushing the Boundaries to Promote Innovation and Achieve Equitable, Patient-Centered Care. Semin Oncol Nurs. 2024 Jun;40(3):151635. doi: 10.1016/j.soncn.2024.151635. Epub 2024 Apr 18. PMID: 38641522.

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Risk-reducing mastectomy and breast cancer mortality in women with a BRCA1 or BRCA2 pathogenic variant: an international analysis

Metcalfe, K., Huzarski, T., Gronwald, J., Kotsopoulos, J., Kim, R., Moller, P., Pal, T., Aeilts, A., Eisen, A., Karlan, B., Bordeleau, L., et al. Hereditary Breast Cancer Clinical Study Group (2024). Risk-reducing mastectomy and breast cancer mortality in women with a BRCA1 or BRCA2 pathogenic variant: an international analysis. British journal of cancer, 130(2), 269–274. https://doi.org/10.1038/s41416-023-02503-8

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Primary outcome reporting in clinical trials for older adults with depression

Rodrigues, M., Oprea, A., Johnson, K., Dufort, A., Sanger, N., Ghiassi, P., Sanger, S., Panesar, B., D'Elia, A., Parpia, S., Samaan, Z., & Thabane, L. (2024). Primary outcome reporting in clinical trials for older adults with depression. BJPsych open, 10(2), e60. https://doi.org/10.1192/bjo.2023.650

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Proton pump inhibitors for gastrointestinal bleeding prophylaxis in critically ill patients: A systematic review protocol

Wang, Y., Heels-Ansdell, D., Ge, L., Parpia, S., Ibrahim, Q., Cook, D., Deane, A., Lauzier, F., Hammond, N., Møller, M. H., Krag, M., Perner, A., & Guyatt, G. H. (2024). Proton pump inhibitors for gastrointestinal bleeding prophylaxis in critically ill patients: A systematic review protocol. Acta anaesthesiologica Scandinavica, 10.1111/aas.14426. Advance online publication. https://doi.org/10.1111/aas.14426

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Long‐term follow‐up of outcomes including progression‐free survival 2 in patients with transplant‐ineligible multiple myeloma in the real‐world practice: A multi‐institutional report from the Canadian Myeloma Research Group (CMRG) database

Kaedbey, Rayan & Reece, Donna & Venner, Christopher & McCurdy, Arleigh & Su, Jiandong & Chu, Michael & Jimenez-Zepeda, Victor & Mian, Hira & Song, Kevin & Sebag, Michael & Stakiw, Julie & White, Darrell & Reiman, Anthony & Aslam, Muhammad & Kotb, Rami & Bergstrom, Debra & Gul, Engin & Leblanc, Richard. (2024). Long‐term follow‐up of outcomes including progression‐free survival 2 in patients with transplant‐ineligible multiple myeloma in the real‐world practice: A multi‐institutional report from the Canadian Myeloma Research Group (CMRG) database. eJHaem. 5. 10.1002/jha2.894.

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Dynamic frailty risk assessment among older adults with multiple myeloma: A population-based cohort study

Mian H, Wildes TM, Vij R, Pianko MJ, Major A, Fiala MA. Blood Cancer Journal. 2023 May;13(1):76.

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Impact of Frailty on Health Care Resource Utilization and Costs of Care in Myelodysplastic Syndromes

Mozessohn L, Li Q, Liu N, Leber B, Khalaf D, Sabloff M, Christou G, Yee K, Chodirker L, Parmentier A, Siddiqui M, Mamedov A, Zhang L, Liu Y, Earle CC, Cheung MC, Mittmann N, Buckstein R. Impact of Frailty on Health Care Resource Utilization and Costs of Care in Myelodysplastic Syndromes. JCO Oncology Practice. 2023 April; 19(4) 559-569.

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Adjuvant therapy for renal cell carcinoma: 2023 Canadian Kidney Cancer Forum consensus statement

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Competency-Based Medical Education in Canadian Radiation Oncology Residency Training: an Institutional Implementation Pilot Study

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Prognostic value of translocation 11;14 in patients with relapsed/refractory myeloma receiving anti-CD38 therapy

Mohyuddin GR, Chakraborty R, Calip GS, Ascha MS, Wang X, Rubinstein SM, Tuchman S, Costa L, Haaland B, Giri S, Mian H, Fonseca R, Sborov D. Prognostic value of translocation 11;14 in patients with relapsed/refractory myeloma receiving anti-CD38 therapy. Blood Cancer J. 2022 Dec 16;12(12):168. doi: 10.1038/s41408-022-00769-4. PMID: 36526617; PMCID: PMC9758218.

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A Survey of Patient Experience in CML: American and Canadian Perspectives

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Developing a Data and Analytics Platform to Enable a Breast Cancer Learning Health System at a Regional Cancer Center.

Petch J, Kempainnen J, Pettengell C, Aviv S, Butler B, Pond G, Saha A, Bogach J, Allard-Coutu A, Sztur P, Ranisau J, Levine M. Developing a Data and Analytics Platform to Enable a Breast Cancer Learning Health System at a Regional Cancer Center. JCO Clin Cancer Inform. 2023 Mar;7:e2200182

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Generative AI for brain image computing and brain network computing: a review

Gong C, Jing C, Chen X, Pun CM, Huang G, Saha A, Nieuwoudt M, Li HX, Hu Y, Wang S. Generative AI for brain image computing and brain network computing: a review. Front Neurosci. 2023 Jun 13;17:1203104.

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Outcome of carfilzomib/pomalidomide?based regimens after daratumumab?based treatment in relapsed multiple myeloma: A Canadian Myeloma Research Group Database analysis

LeBlanc R, Mian H, Reece D, Su J, Masih-Khan E, Chu M, Jimenez-Zepeda V, Sebag M, Song K, Louzada M, Kotb R, Visram A, White D, Stakiw J, Reiman A, Aslam M, Bergstrom D, Kaedbey R, Gul E, Venner C. Outcome of carfilzomib/pomalidomide-based regimens after daratumumab-based treatment in relapsed multiple myeloma: A Canadian Myeloma Research Group Database analysis. Eur J Haematol. 2023 Nov;111(5):815-823.

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Magnetic Resonance Imaging–Targeted Versus Systematic Prostate Biopsies: 2-year Follow-up of a Prospective Randomized Trial (PRECISE)

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Prostate-Specific Membrane Antigen (PSMA) Expression Predicts Need for Early Treatment in Prostate Cancer Patients Managed with Active Surveillance

Ahmadi E, Wang S, Gouran-Savadkoohi M, Douvi G, Isfahanian N, Tsakiridis N, Faught BE, Cutz JC, Sur M, Chawla S, Pond GR, Steinberg GR, Brown I, Tsakiridis T. Prostate-Specific Membrane Antigen (PSMA) Expression Predicts Need for Early Treatment in Prostate Cancer Patients Managed with Active Surveillance. Int J Mol Sci. 2023 Nov 7;24(22):16022.

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Cardiac Interventions in Patients With Active, Advanced Solid and Hematologic Malignancies JACC: CardioOncology State-of-the-Art Review

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Proton Therapy Mediates Dose Reductions to Critical Brain Organs at Risk Which are Associated with Better Cognition in Children with Medulloblastoma

Sienna J, Kahalley LS, Mabbott D, Grosshans D, Santiago AT, Paulino ADC, Merchant TE, Manzar GS, Dama H, Hodgson DC, Chintagumpala M, Okcu MF, Whitehead WE, Laperriere N, Ramaswamy V, Bartels U, Tabori U, Bennett JM, Das A, Craig T, Tsang DS. Proton Therapy Mediates Dose Reductions to Brain Structures Associated With Cognition in Children With Medulloblastoma. Int J Radiat Oncol Biol Phys. 2024 May 1;119(1):200-207. doi: 10.1016/j.ijrobp.2023.11.035. Epub 2023 Nov 30. PMID: 38040059; PMCID: PMC11023754.

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Dose Reductions to Critical Brain Organs-at-Risk and Better Cognition in Children with Medulloblastoma Receiving Proton Therapy

Sienna, J., Kahalley, L., Mabbott, D., Grosshans, D. R., Santiago, A. T., Paulino, A. C., Manzar, G. S., Dama, H., Chintagumpala, M., Okcu, F., Whitehead, W., Ramaswamy, V., Laperriere, N. J., Merchant, T. E., Craig, T., & Tsang, D. S. C. (2023). Dose reductions to critical brain organs-at-risk and better cognition in children with medulloblastoma receiving proton therapy. International Journal of Radiation Oncology*Biology*Physics, 117(2). https://doi.org/10.1016/j.ijrobp.2023.06.536

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PCSK9 facilitates melanoma pathogenesis via a network regulating tumor immunity

Gu Y, Lin X, Dong Y, Wood G, Seidah NG, Werstuck G, Major P, Bonert M, Kapoor A, Tang D. PCSK9 facilitates melanoma pathogenesis via a network regulating tumor immunity. J Exp Clin Cancer Res. 2023 Jan 2;42(1):2. doi: 10.1186/s13046-022-02584-y. PMID: 36588164; PMCID: PMC9806914.

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PDP1 is a key metabolic gatekeeper and modulator of drug resistance in FLT3-ITD-positive acute myeloid leukemia

Alshamleh I, Kurrle N, Makowka P, Bhayadia R, Kumar R, Süsser S, Seibert M, Ludig D, Wolf S, Koschade SE, Stoschek K, Kreitz J, Fuhrmann DC, Toenges R, Notaro M, Comoglio F, Schuringa JJ, Berg T, et al. PDP1 is a key metabolic gatekeeper and modulator of drug resistance in FLT3-ITD-positive acute myeloid leukemia. Leukemia. 2023 Dec;37(12):2367-2382. doi: 10.1038/s41375-023-02041-5. Epub 2023 Nov 7. PMID: 37935978; PMCID: PMC10681906.

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Prophylaxis extension for venous thromboembolism after major abdominal and pelvic surgery for cancer (prevent): Quality improvement transitioned into a cohort study

McKechnie T, Tywonek K, Simunovic M, Serrano PE. Prophylaxis extension for venous thromboembolism after major abdominal and pelvic surgery for cancer (prevent): Quality improvement transitioned into a cohort study. Surgery. 2022 July; 172(1) 234-240

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Cost Effectiveness Analysis of Radiofrequency Ablation (RFA) Versus Stereotactic Body Radiotherapy (SBRT) for Early Stage Renal Cell Carcinoma (RCC)

Donovan EK, Xie F, Louie AV, Chu W, Siva S, Kapoor A, Swaminath A. Cost Effectiveness Analysis of Radiofrequency Ablation (RFA) Versus Stereotactic Body Radiotherapy (SBRT) for Early Stage Renal Cell Carcinoma (RCC). Clinical Genitourinary Cancer. 2022 Oct; 20(5):e353-e361

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Artichoke phytocomplex modulates serum microRNAs in patients exposed to asbestos: a first step of a phase II clinical trial

Muti P, Sacconi A, Pulito C, Orlandi G, Donzelli S, Morrone A, Jiulian J, Cox GP, Kolb M, Pond G, Kavsak P, Levine MN, Blandino G, Strano S. Artichoke phytocomplex modulates serum microRNAs in patients exposed to asbestos: a first step of a phase II clinical trial. Journal of Experimental & Clinical Cancer Research. 2022 Aug 20;41(1):255.

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Examining patient perspectives on sarcoma surveillance: The Sarcoma Surveillance Survey

Tepper SC, Holten AK, Jeffe DB, England PH, Hong ZL, Pérez M, Ghert M, Hirbe AC, Cipriano CA. Examining patient perspectives on sarcoma surveillance: The Sarcoma Surveillance Survey. Surg Oncol. 2022 Dec;45:101861

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First Pan-Canadian Consensus Recommendations for Proton Beam Therapy Access in Canada

Mitera G, Tsang D, McCurdy B, Goddard K, Ebacher A, Craig T, Greenland J, Kentish S, Koul R, Logie N, Morneau M, Morrison A, Pan L, Pantarotto J, Foxcroft S, Sussman J, Thompson R, Tyldesley S, Wright P, Hicks S, Brown E, Patel S; CAPCA pan-Canadian PBT Working Group. Pan-Canadian consensus recommendations for proton beam therapy access in Canada. Radiother Oncol. 2022 Nov;176:228-233. doi: 10.1016/j.radonc.2022.10.004. Epub 2022 Oct 11. PMID: 36228758.

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Racial Disparities in Patients with Stage IIIC Endometrial Cancer

Patrich T, Wang Y, Elshaikh MA, Zhu S, Damast S, Li JY, Fields EC, Beriwal S, Keller A, Kidd EA, Usoz M, Jolly S, Jaworski E, Leung EW, Donovan E, Taunk NK, Chino JP, Russo AL, Lea JS, Lee LJ, Albuquerque K, Hathout L. Racial Disparities in Patients with Stage IIIC Endometrial Cancer. International Journal of Radiation Oncology. Nov 2023; 114(3);s273-s274

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Percées dans la prise en charge de l’hypernéphrome

Cardenas LM, Sigurdson S, Wallis CJD, Lalani AK, Swaminath A. Percées dans la prise en charge de l’hypernéphrome. CMAJ. 2024 May 5;196(17):E601-E607. French. doi: 10.1503/cmaj.230356-f. PMID: 38719217; PMCID: PMC11073830.

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Ductal carcinoma in situ of the breast: finding the balance between overtreatment and undertreatment

Delaloge S, Khan SA, Wesseling J, Whelan T. Ductal carcinoma in situ of the breast: finding the balance between overtreatment and undertreatment. Lancet. 2024 May 9:S0140-6736(24)00425-2. doi: 10.1016/S0140-6736(24)00425-2. Epub ahead of print. PMID: 38735296.

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Advances in the management of renal cell carcinoma

Luisa M. Cardenas, Samantha Sigurdson, Christopher J.D. Wallis, Aly-Khan Lalani, Anand Swaminath CMAJ Feb 2024, 196 (7) E235-E240; DOI: 10.1503/cmaj.230356

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How a Canadian federal organization integrated synoptic reporting and quality improvement tools to drive a national learning health system in cancer surgery.

Arnaout, A., Brehaut, J., Hillis, C., Presseau, J., Seely, A., Daly, C., Stuart, G., & Fung Kee Fung, M. (2024). How a Canadian federal organization integrated synoptic reporting and quality improvement tools to drive a national learning health system in cancer surgery. Healthcare management forum, 8404704241236761. Advance online publication. https://doi.org/10.1177/08404704241236761

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Risk Factors for Hospital Readmission Following Noncardiac Surgery: International Cohort Study

McGillion, Michael H. RN, PhD*,†; Borges, Flavia K. MD, PhD†,‡; Conen, David MD, MPH†,‡,§; Sessler, Daniel I. MD‖; Coleman, Brenda L. RN, PhD¶,#; Marcucci, Maura MD, MSc†,‡,§; Ouellette, Carley RN, MSc*; Bird, Marissa RN, PhD*; Whitmore, Carly RN, PhD*; Henry, Shaunattonie RN, PhD*; Ofori, Sandra MD, MSc†,§; Pettit, Shirley M. RN†; Bedini, Deborah M. RN, MHS**; Gauthier, Leslie P. MScT††; Lounsbury, Jennifer RN(EC), MN*,††; Carter, Nancy M. RN, PhD*; Tandon, Vikas MD‡; Patel, Ameen MD‡,††; Cafaro, Teresa MD, MSc†,§; Simunovic, Marko R. MD††,‡‡; Harlock, John A. MD**,‡‡; Heels-Ansdell, Diane MSc§; Elias, Fadi MD, MS‡‡; Rapanos, Theodore MD‡‡; Forbes, Shawn MD††,‡‡; Peter, Elizabeth RN, PhD§§; Watt-Watson, Judy RN, PhD§§; Metcalfe, Kelly RN, PhD§§; Carroll, Sandra L. RN, PhD*,†; Devereaux, Philip J. MD, PhD†,‡,§. Risk Factors for Hospital Readmission Following Noncardiac Surgery: International Cohort Study. Annals of Surgery 5(2):p e417, June 2024. | DOI: 10.1097/AS9.0000000000000417

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MP36-13 ASSOCIATION BETWEEN THE SARCOMATOID STATUS AND PERCENTAGE OF SARCOMATOID ON THE CLINICAL OUTCOMES OF LOCALIZED RENAL CELL CARCINOMA POST NEPHRECTOMY

Soytas M, Bou-Nehme Sawaya G, Dragomir A, Hesswani C, Finelli A, Wood L, et al. MP36-13 ASSOCIATION BETWEEN THE SARCOMATOID STATUS AND PERCENTAGE OF SARCOMATOID ON THE CLINICAL OUTCOMES OF LOCALIZED RENAL CELL CARCINOMA POST NEPHRECTOMY. Journal of Urology [Internet]. 2024 May 1 [cited 2024 Jun 19];211(5S):e597. Available from: https://doi.org/10.1097/01.JU.0001008612.93052.9d.13

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Surgical margin status in relation to surgical approach in the management of early-stage cervical Cancer: A Canadian cervical Cancer collaborative (4C) study

Piedimonte S, Helpman L, Pond G, Nelson G, Kwon J, Altman A, Feigenberg T, Elit L, Lau S, Sabourin J, Samouelian V, Willows K, Aubrey C, Jang J-H, Teo-Fortin L-A, Cockburn N, Saunders N-B, Shamiya S, Vicus D, Plante M, Collaborative OBOTCCCC. Gynecologic Oncology. 2023 May 3;174:21-27.

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Long-term outcomes and effects of hypofractionated radiotherapy in microinvasive breast cancer: Analysis from a randomized trial

Goldberg M, Parpia S, Rakovitch E, Chang L, Bowen J, Lukka H, Perera F, Fyles A, Wright J, Sussman J, Whelan T. Long-term outcomes and effects of hypofractionated radiotherapy in microinvasive breast cancer: Analysis from a randomized trial. The Breast. 2023 April; 68. 189-193.

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Immune-Checkpoint Induced Skin Toxicity Masked as Squamous Cell Carcinoma: Case Report on Mimickers of Dermatological Toxicity with PD-1 Inhibition

Chan SWS, Shukla R, Ramsay J, McWhirter E, Barnfield P, Juergens RA. Immune-Checkpoint Induced Skin Toxicity Masked as Squamous Cell Carcinoma: Case Report on Mimickers of Dermatological Toxicity with PD-1 Inhibition. Current Oncology. 2023 April; 30(5):4527-4537.

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Real-world utilization and outcomes of docetaxel among older men with metastatic prostate cancer: a retrospective population-based cohort study in Canada

Shayegan B, Wallis CJD, Hamilton RJ, Morgan SC, Cagiannos I, Basappa NS, Ferrario C, Gotto GT, Fernandes R, Roy S, Noonan KL, Niazi T, Hotte SJ, Saad F, Hew H, Park-Wyllie L, Chan KFY, Malone S. Real-world utilization and outcomes of docetaxel among older men with metastatic prostate cancer: a retrospective population-based cohort study in Canada. Prostate Cancer and Prostatic Disease. 2023 Mar; 26(1) 74-79

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Cardiac Morbidity Following Chemoradiation in Stage III Non-small Cell Lung Cancer Patients: A Population-Based Cohort Study

Donovan EK, Pond GR, Seow H, Ellis PM, Swaminath A. Cardiac Morbidity Following Chemoradiation in Stage III Non-small Cell Lung Cancer Patients: A Population-Based Cohort Study. Clin Oncol (R Coll Radiol). 2023 Feb;35(2):e182-e188. doi: 10.1016/j.clon.2022.11.019. Epub 2022 Dec 17.

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Contemporary real-world radiotherapy outcomes of unresected locally advanced non-small cell lung cancer

Gouran-Savadkoohi M, Mesci A, Pond GR, Swaminath A, Quan K, Wright J, Tsakiridis T. Contemporary real-world radiotherapy outcomes of unresected locally advanced non-small cell lung cancer. J Thorac Dis. 2023 Feb 28;15(2):423-433

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A double-blinded, randomized trial comparing surgeon-administered transversus abdominis plane block with placebo after midline laparotomy in gynecologic oncology surgery

Bernard L, Lavecchia M, Trepanier G, Mah S, Pokoradi A, McGinnis JM, Alyafi M, Glezerson B, Nguyen J, Carlson V, Helpman L, Elit L, Jimenez W, Eiriksson L, Reade CJ. A double-blinded, randomized trial comparing surgeon-administered transversus abdominis plane block with placebo after midline laparotomy in gynecologic oncology surgery. Am J Obstet Gynecol. 2023 May;228(5):553.e1-553.e8.

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Very low energy diets prior to bariatric surgery may reduce postoperative morbidity: a systematic review and meta-analysis of randomized controlled trials

McKechnie T, Lee Y, Dionne J, Doumouras A, Parpia S, Bhandari M, Eskicioglu C. Very low energy diets prior to bariatric surgery may reduce postoperative morbidity: a systematic review and meta-analysis of randomized controlled trials. Front Nutr. 2023 Jun 20;10:1211575.

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A Cancer Care Ontario Consensus-Based Organizational Guideline for the Planning and Delivery of Spine Stereotactic Body Radiation Therapy Treatment in Ontario

Sahgal A, Kellett S, Nguyen T, Maralani P, Greenspoon J, Linden K, Pearce A, Siddiqi F, Ruschin M; Spine Expert Panel. A Cancer Care Ontario Consensus-Based Organizational Guideline for the Planning and Delivery of Spine Stereotactic Body Radiation Therapy Treatment in Ontario. Pract Radiat Oncol. 2023 Nov-Dec;13(6):499-509.

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Long-Term Follow-Up Analysis of NRG Oncology RTOG 0415: A Randomized Phase III Non-Inferiority Study Comparing Two Fractionation Schedules in Patients with Favorable-Risk Prostate Cancer

Lee WR, Dignam JJ, Amin M, Bruner DW, Low D, Swanson GP, et al. Long-term follow-up analysis of nrg oncology rtog 0415: a randomized phase iii non-inferiority study comparing two fractionation schedules in patients with favorable-risk prostate cancer. International Journal of Radiation Oncology. 2023 Oct 1 ;117(2):S3–4.

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Patient reported symptom burden amongst immigrant and Canadian long-term resident women undergoing breast cancer surgery

Parvez E, Chu M, Kirkwood D, Doumouras A, Levine M, Bogach J. Patient reported symptom burden amongst immigrant and Canadian long-term resident women undergoing breast cancer surgery. Breast Cancer Research and Treatment. 199(3):553-563. doi:10.1007/s10549-023-06938-8

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Primary care nursing competencies in Canadian undergraduate nursing programs: A national cross-sectional survey

Lukewich J, Mathews M, Poitras ME, Tranmer J, Martin-Misener R, Bryant-Lukosius D, Aubrey-Bassler K, Klassen T, Curnew D, Bulman D, Leamon T, Ryan D. Primary care nursing competencies in Canadian undergraduate nursing programs: A national cross-sectional survey. Nurse Educ Pract. 2023 Aug;71:103738. doi: 10.1016/j.nepr.2023.103738. Epub 2023 Aug 3. PMID: 37549469.

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Evaluating the Utility and Privacy of Synthetic Breast Cancer Clinical Trial Data Sets

El Kababji S, Mitsakakis N, Fang X, Beltran-Bless AA, Vandermeer L, Radhakrishnan D, Pond G, et al. Evaluating the Utility and Privacy of Synthetic Breast Cancer Clinical Trial Data Sets. JCO Clin Cancer Inform. 2023 Sep;7:e2300116. doi: 10.1200/CCI.23.00116. PMID: 38011617; PMCID: PMC10703127.

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CN57 Patients, informal caregivers and healthcare professionals experience in adoptive cell therapies: An experience-based co-design study (EBCD-ACT)

Canova, N., Graber, N., Corbière, T., Bosisio, F., Kaufmann, A., Bryant-Lukosius, D., Eicher, M., & Colomer-Lahiguera, S. (2023). CN57 patients, informal caregivers and healthcare professionals experience in adoptive cell therapies: An experience-based co-design study (EBCD-act). Annals of Oncology, 34. https://doi.org/10.1016/j.annonc.2023.09.1651

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Increasing palliative care capacity in primary care: study protocol of a cluster randomized controlled trial of the CAPACITI training program

Seow H, Bainbridge D, Winemaker S, Stajduhar K, Pond G, Kortes-Miller K, Marshall D, Kilbertus F, Myers J, Steinberg L, Incardona N, Levine O, Pereira J. Increasing palliative care capacity in primary care: study protocol of a cluster randomized controlled trial of the CAPACITI training program. BMC Palliat Care. 2023 Jan 5;22(1):2. doi: 10.1186/s12904-022-01124-x. PMID: 36604714; PMCID: PMC9813458.

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Liver Metastases and Immune Checkpoint Inhibitor Efficacy in Patients With Refractory Metastatic Colorectal Cancer

Chen EX, Loree JM, Titmuss E, Jonker DJ, Kennecke HF, Berry S, Couture F, Ahmad CE, Goffin JR, et al. Liver Metastases and Immune Checkpoint Inhibitor Efficacy in Patients With Refractory Metastatic Colorectal Cancer: A Secondary Analysis of a Randomized Clinical Trial. JAMA Netw Open. 2023 Dec 1;6(12):e2346094. doi: 10.1001/jamanetworkopen.2023.46094. PMID: 38051531; PMCID: PMC10698621.

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Outcomes of Radiation Therapy Plus Immunotherapy in Metastatic Renal Cell Carcinoma: Results From the Canadian Kidney Cancer Information System

Nguyen EK, Lalani AKA, Ghosh S, Basappa NS, Kapoor A, Hansen AR, Kollmannsberger C, Heng D, Wood LA, Castonguay V, Soulières D, Winquist E, Canil C, Graham J, Bjarnason GA, Breau RH, Pouliot F, Swaminath A. Outcomes of Radiation Therapy Plus Immunotherapy in Metastatic Renal Cell Carcinoma: Results From the Canadian Kidney Cancer Information System. Advances in Radiation Oncology. 2022 July; 7(4) 100899

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Recommendations for the implementation of genetic testing for metastatic prostate cancer patients in Canada

Selvarajah S, Schrader KA, Kolinsky MP, Rendon RA, El Hallani S, Fleshner NE, Hotte SJ, Lorentz J, Panabaker K, Perrier R, Pouliot F, Spatz A, Yip S, Chi KN. Recommendations for the implementation of genetic testing for metastatic prostate cancer patients in Canada. Canadian Urological Association Journal. 2022 Nov; 16(11): e516-e522

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ASO Visual Abstract: Neoadjuvant Chemotherapy and Endoprosthetic Reconstruction for Lower-Extremity Sarcomas—Does Timing Impact Complication Rates?

Gazendam AM, Schneider P, Spiguel A, Ghert M. ASO Visual Abstract: Neoadjuvant Chemotherapy and Endoprosthetic Reconstruction for Lower-Extremity Sarcomas—Does Timing Impact Complication Rates. Annals of Surgical Oncology. 2022 Nov;29(12):7319.

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Surgical, Radiation, and Systemic Treatments of Patients With Thymic Epithelial Tumors: A Clinical Practice Guideline

Falkson CB, Vella ET, Ellis PM, Maziak DE, Ung YC, Yu E. Surgical, Radiation, and Systemic Treatments of Patients With Thymic Epithelial Tumors: A Clinical Practice Guideline. J Thorac Oncol. 2022 Nov;17(11):1258-1275

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High transferrin saturation predicts inferior clinical outcomes in patients with myelodysplastic syndromes

Teichman J, Geddes M, Zhu N, Keating MM, Sabloff M, Christou G, Leber B, Khalaf D, St-Hilaire E, Finn N, Shamy A, Yee KWL, Storring JM, Nevill TJ, Delage R, Elemary M, Banerji V, Houston B, Mozessohn L, Chodirker L, Zhang L, Siddiqui M, Parmentier A, Leitch HA, Buckstein RJ. High transferrin saturation predicts inferior clinical outcomes in patients with myelodysplastic syndromes. Haematologica. 2023 Feb 1;108(2):532-542.

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Development of a Support Vector Machine-Based Tool for Survival Prediction after Stereotactic Body Radiotherapy for Liver Metastases Using Multi-Institutional Data

Nam K, Arsenault T, Baydoun A, Amini A, Saieed G, Zeidane RA, Bhat SS, Bailey L, Sachdeva R, Chow R, Chu W, Liu H, Chung HT, Schellenberg D, Swaminath A, Lock MI, Podder TK, Biswas T.Development of a Support Vector Machine-Based Tool for Survival Prediction after Stereotactic Body Radiotherapy for Liver Metastases Using Multi-Institutional Data. International Journal of Radiation Oncology. 2022 Nov: 114(3): e1222

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Compelling evidence from meta-epidemiological studies demonstrates overestimation of effects in randomized trials that fail to optimize randomization and blind patients and outcome assessors

Wang Y, Parpia S, Couban R, Wang Q, Armijo-Olivo S, Bassler D, Briel M, Brignardello-Petersen R, Gluud LL, Keitz SA, Letelier LM, Ravaud P, Schulz KF, Siemieniuk RAC, Zeraatkar D, Guyatt GH. Compelling evidence from meta-epidemiological studies demonstrates overestimation of effects in randomized trials that fail to optimize randomization and blind patients and outcome assessors. J Clin Epidemiol. 2024 Jan;165:111211. doi: 10.1016/j.jclinepi.2023.11.001. Epub 2023 Nov 7. PMID: 37939743.

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Adaptive clinical trials in surgery: A scoping review of methodological and reporting quality

Staibano P, Oulousian E, McKechnie T, Thabane A, Luo S, Gupta MK, Zhang H, Pasternak JD, Au M, Parpia S, Young JEMT, Bhandari M. Adaptive clinical trials in surgery: A scoping review of methodological and reporting quality. PLoS One. 2024 May 28;19(5):e0299494. doi: 10.1371/journal.pone.0299494. PMID: 38805454; PMCID: PMC11132449.

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Development of a Comprehensive Model for Cancer Symptom Care for Women With Ovarian or Endometrial Cancer

Christiansen, Mille & Jarden, Mary & Colomer-Lahiguera, Sara & Eicher, Manuela & Bryant-Lukosius, Denise & Mirza, Mansoor & Pappot, Helle & Piil, Karin. (2024). Development of a Comprehensive Model for Cancer Symptom Care for Women With Ovarian or Endometrial Cancer. Cancer Care Research Online. 4. e054. 10.1097/CR9.0000000000000054.

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Measurement of adverse cosmesis in breast cancer: A deep learning approach

Saha, A., Levine, M., Kong, I., Parvez, E., & Whelan, T. (2024). Measurement of adverse cosmesis in breast cancer: A deep learning approach. Expert Systems with Applications, 238, 122209. https://doi.org/10.1016/j.eswa.2023.122209

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